Term Information [More information on MHC class I peptide loading complex]

Accession
GO:0042824
Name
MHC class I peptide loading complex
Ontology
cellular_component
Synonyms
None
Definition
A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. Source: GOC:jl, PMID:10631934
Comment
Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi.
History
See term history for GO:0042824 at QuickGO
Subset
goslim_pir
Community
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Feedback
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Contacting server...
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Graph of GO:0042824 from QuickGO

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Ancestors of MHC class I peptide loading complex (GO:0042824)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) cytoplasmic part (GO:0044444)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) endomembrane system (GO:0012505)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) membrane (GO:0016020)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) organelle part (GO:0044422)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum (GO:0005783)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intracellular organelle part (GO:0044446)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) membrane part (GO:0044425)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) organelle membrane (GO:0031090)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) bounding membrane of organelle (GO:0098588)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum part (GO:0044432)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intrinsic component of membrane (GO:0031224)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) nuclear outer membrane-endoplasmic reticulum membrane network (GO:0042175)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum membrane (GO:0005789)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) integral component of membrane (GO:0016021)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intrinsic component of organelle membrane (GO:0031300)
MHC class I peptide loading complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) integral component of organelle membrane (GO:0031301)
MHC class I peptide loading complex [Inferred part_of relation] part_of (inferred) intrinsic component of endoplasmic reticulum membrane (GO:0031227)
MHC class I peptide loading complex [is_a relation] is_a  protein complex (GO:0043234)
MHC class I peptide loading complex [part_of relation] part_of  integral component of endoplasmic reticulum membrane (GO:0030176)
MHC class I peptide loading complex [is_a relation] is_a  membrane protein complex (GO:0098796)
Children of MHC class I peptide loading complex (GO:0042824)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TAP complex (GO:0042825) [part_of relation] part_of  MHC class I peptide loading complex
None.