Term Information [More information on negative regulation of tumor necrosis factor biosynthetic process]

Accession
GO:0042536
Name
negative regulation of tumor necrosis factor biosynthetic process
Ontology
biological_process
Synonyms
down regulation of tumor necrosis factor biosynthetic process, down-regulation of tumor necrosis factor biosynthetic process, downregulation of tumor necrosis factor biosynthetic process, negative regulation of TNF alpha biosynthesis, negative regulation of TNF alpha biosynthetic process, negative regulation of TNF biosynthesis, negative regulation of TNF biosynthetic process, negative regulation of TNF-alpha biosynthesis, negative regulation of TNF-alpha biosynthetic process, negative regulation of tumor necrosis factor anabolism, negative regulation of tumor necrosis factor biosynthesis, negative regulation of tumor necrosis factor formation, negative regulation of tumor necrosis factor synthesis, negative regulation of tumor necrosis factor-alpha biosynthesis, negative regulation of tumor necrosis factor-alpha biosynthetic process, inhibition of tumor necrosis factor biosynthetic process
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. Source: PMID:10891884, GOC:jl
Comment
Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').
History
See term history for GO:0042536 at QuickGO
Subset
None
Community
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Ancestors of negative regulation of tumor necrosis factor biosynthetic process (GO:0042536)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) biological_process (GO:0008150)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) metabolic process (GO:0008152)
negative regulation of tumor necrosis factor biosynthetic process [is_a relation] is_a  biological regulation (GO:0065007)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) multicellular organismal process (GO:0032501)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) organic substance metabolic process (GO:0071704)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) single-organism process (GO:0044699)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) biosynthetic process (GO:0009058)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cellular process (GO:0009987)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) macromolecule metabolic process (GO:0043170)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) primary metabolic process (GO:0044238)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) single-multicellular organism process (GO:0044707)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cellular metabolic process (GO:0044237)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cytokine production (GO:0001816)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of biological process (GO:0048519)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) organic substance biosynthetic process (GO:1901576)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) protein metabolic process (GO:0019538)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of metabolic process (GO:0019222)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of multicellular organismal process (GO:0051239)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cellular biosynthetic process (GO:0044249)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cytokine metabolic process (GO:0042107)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) macromolecule biosynthetic process (GO:0009059)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of cellular process (GO:0048523)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of metabolic process (GO:0009892)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of multicellular organismal process (GO:0051241)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of biosynthetic process (GO:0009889)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of cellular metabolic process (GO:0031323)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of cytokine production (GO:0001817)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of macromolecule metabolic process (GO:0060255)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of primary metabolic process (GO:0080090)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) tumor necrosis factor superfamily cytokine production (GO:0071706)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) cytokine biosynthetic process (GO:0042089)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of biosynthetic process (GO:0009890)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of cellular metabolic process (GO:0031324)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of cytokine production (GO:0001818)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of macromolecule metabolic process (GO:0010605)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of cellular biosynthetic process (GO:0031326)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of macromolecule biosynthetic process (GO:0010556)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of protein metabolic process (GO:0051246)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)
negative regulation of tumor necrosis factor biosynthetic process [Inferred negatively_regulates relation] negatively_regulates (inferred) tumor necrosis factor production (GO:0032640)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of cellular biosynthetic process (GO:0031327)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of macromolecule biosynthetic process (GO:0010558)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of protein metabolic process (GO:0051248)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of cytokine biosynthetic process (GO:0042035)
negative regulation of tumor necrosis factor biosynthetic process [Inferred is_a relation] is_a (inferred) regulation of tumor necrosis factor production (GO:0032680)
negative regulation of tumor necrosis factor biosynthetic process [negatively_regulates relation] negatively_regulates  tumor necrosis factor biosynthetic process (GO:0042533)
negative regulation of tumor necrosis factor biosynthetic process [is_a relation] is_a  negative regulation of cytokine biosynthetic process (GO:0042036)
negative regulation of tumor necrosis factor biosynthetic process [is_a relation] is_a  negative regulation of tumor necrosis factor production (GO:0032720)
negative regulation of tumor necrosis factor biosynthetic process [is_a relation] is_a  regulation of tumor necrosis factor biosynthetic process (GO:0042534)

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