Term Information [More information on aspartic endopeptidase activity, intramembrane cleaving]

Accession
GO:0042500
Name
aspartic endopeptidase activity, intramembrane cleaving
Ontology
molecular_function
Synonyms
None
Definition
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. Source: ISBN:0198506732, GOC:jl
Comment
Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases.
History
See term history for GO:0042500 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0042500 from QuickGO

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Ancestors of aspartic endopeptidase activity, intramembrane cleaving (GO:0042500)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
aspartic endopeptidase activity, intramembrane cleaving [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) aspartic-type peptidase activity (GO:0070001)
aspartic endopeptidase activity, intramembrane cleaving [Inferred is_a relation] is_a (inferred) endopeptidase activity (GO:0004175)
aspartic endopeptidase activity, intramembrane cleaving [is_a relation] is_a  aspartic-type endopeptidase activity (GO:0004190)

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