Term Information [More information on hydroxymethylglutaryl-CoA reductase activity]

Accession
GO:0042282
Name
hydroxymethylglutaryl-CoA reductase activity
Ontology
molecular_function
Synonyms
(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating), 3-hydroxy-3-methylglutaryl coenzyme A reductase activity, hydroxymethylglutaryl-CoA reductase (NADH) activity, 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity, HMG-CoA reductase activity, beta-hydroxy-beta-methylglutaryl CoA-reductase activity, beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity, hydroxymethylglutaryl coenzyme A reductase activity
Definition
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH. Source: EC:1.1.1.88, RHEA:14836
Comment
None
History
See term history for GO:0042282 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0042282 from QuickGO

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Ancestors of hydroxymethylglutaryl-CoA reductase activity (GO:0042282)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hydroxymethylglutaryl-CoA reductase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
hydroxymethylglutaryl-CoA reductase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
hydroxymethylglutaryl-CoA reductase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
hydroxymethylglutaryl-CoA reductase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
hydroxymethylglutaryl-CoA reductase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
hydroxymethylglutaryl-CoA reductase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
hydroxymethylglutaryl-CoA reductase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
hydroxymethylglutaryl-CoA reductase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
hydroxymethylglutaryl-CoA reductase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
hydroxymethylglutaryl-CoA reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

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