Term Information [More information on Kit signaling pathway]

Accession
GO:0038109
Name
Kit signaling pathway
Ontology
biological_process
Synonyms
Kit signalling pathway, SCF signaling pathway, stem cell factor receptor signaling pathway, stem cell factor signaling pathway
Definition
A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell. Source: PMID:16129412, GOC:signaling, GOC:nhn
Comment
None
History
See term history for GO:0038109 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0038109 from QuickGO

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Ancestors of Kit signaling pathway (GO:0038109)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Kit signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
Kit signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to chemical stimulus (GO:0070887)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) response to organic substance (GO:0010033)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) cell surface receptor signaling pathway (GO:0007166)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to organic substance (GO:0071310)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) response to cytokine (GO:0034097)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to cytokine stimulus (GO:0071345)
Kit signaling pathway [Inferred is_a relation] is_a (inferred) enzyme linked receptor protein signaling pathway (GO:0007167)
Kit signaling pathway [Inferred part_of relation] part_of (inferred) response to stem cell factor (GO:0036215)
Kit signaling pathway [part_of relation] part_of  cellular response to stem cell factor stimulus (GO:0036216)
Kit signaling pathway [is_a relation] is_a  cytokine-mediated signaling pathway (GO:0019221)
Kit signaling pathway [is_a relation] is_a  transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)
Children of Kit signaling pathway (GO:0038109)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of Kit signaling pathway (GO:1900235) [negatively_regulates relation] negatively_regulates  Kit signaling pathway
positive regulation of Kit signaling pathway (GO:1900236) [positively_regulates relation] positively_regulates  Kit signaling pathway
regulation of Kit signaling pathway (GO:1900234) [regulates relation] regulates  Kit signaling pathway
stem cell factor receptor activity (GO:0005020) [part_of relation] part_of  Kit signaling pathway
None.