Term Information [More information on vascular endothelial growth factor signaling pathway]

Accession
GO:0038084
Name
vascular endothelial growth factor signaling pathway
Ontology
biological_process
Synonyms
VEGF signaling, VEGF-activated signaling pathway, vascular endothelial growth factor signalling pathway
Definition
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Source: GOC:signaling, PR:000007520, PR:000003096, PMID:17470632, PR:000017285, PR:000017284
Comment
In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.
History
See term history for GO:0038084 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0038084 from QuickGO

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Ancestors of vascular endothelial growth factor signaling pathway (GO:0038084)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
vascular endothelial growth factor signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
vascular endothelial growth factor signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to chemical stimulus (GO:0070887)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) response to organic substance (GO:0010033)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) cell surface receptor signaling pathway (GO:0007166)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to organic substance (GO:0071310)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) response to growth factor (GO:0070848)
vascular endothelial growth factor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to growth factor stimulus (GO:0071363)
vascular endothelial growth factor signaling pathway [Inferred is_a relation] is_a (inferred) enzyme linked receptor protein signaling pathway (GO:0007167)
vascular endothelial growth factor signaling pathway [part_of relation] part_of  cellular response to vascular endothelial growth factor stimulus (GO:0035924)
vascular endothelial growth factor signaling pathway [is_a relation] is_a  transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)
Children of vascular endothelial growth factor signaling pathway (GO:0038084)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of vascular endothelial growth factor signaling pathway (GO:1900747) [negatively_regulates relation] negatively_regulates  vascular endothelial growth factor signaling pathway
positive regulation of cell migration by vascular endothelial growth factor signaling pathway (GO:0038089) [is_a relation] is_a  vascular endothelial growth factor signaling pathway
positive regulation of vascular endothelial growth factor signaling pathway (GO:1900748) [positively_regulates relation] positively_regulates  vascular endothelial growth factor signaling pathway
regulation of vascular endothelial growth factor signaling pathway (GO:1900746) [regulates relation] regulates  vascular endothelial growth factor signaling pathway
vascular endothelial growth factor-activated receptor activity (GO:0005021) [part_of relation] part_of  vascular endothelial growth factor signaling pathway
VEGF-activated neuropilin signaling pathway (GO:0038190) [is_a relation] is_a  vascular endothelial growth factor signaling pathway
VEGF-activated platelet-derived growth factor receptor signaling pathway (GO:0038086) [is_a relation] is_a  vascular endothelial growth factor signaling pathway
None.