Term Information [More information on p38MAPK cascade]

Accession
GO:0038066
Name
p38MAPK cascade
Ontology
biological_process
Synonyms
p38 MAPK cascade, p38 cascade
Definition
An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell. Source: PMID:20811974, GOC:signaling
Comment
None
History
See term history for GO:0038066 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0038066 from QuickGO

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Ancestors of p38MAPK cascade (GO:0038066)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
p38MAPK cascade [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
p38MAPK cascade [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
p38MAPK cascade [Inferred occurs_in relation] occurs_in (inferred) cellular_component (GO:0005575)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) macromolecule modification (GO:0043412)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) phosphorus metabolic process (GO:0006793)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
p38MAPK cascade [Inferred occurs_in relation] occurs_in (inferred) cell (GO:0005623)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) cellular protein metabolic process (GO:0044267)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) phosphate-containing compound metabolic process (GO:0006796)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) protein modification process (GO:0036211)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
p38MAPK cascade [Inferred occurs_in relation] occurs_in (inferred) cell part (GO:0044464)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) cellular protein modification process (GO:0006464)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) phosphorylation (GO:0016310)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
p38MAPK cascade [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
p38MAPK cascade [Inferred occurs_in relation] occurs_in (inferred) intracellular (GO:0005622)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) protein phosphorylation (GO:0006468)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) response to stress (GO:0006950)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) single-organism metabolic process (GO:0044710)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) cellular response to stress (GO:0033554)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) intracellular signal transduction (GO:0035556)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) signal transduction by protein phosphorylation (GO:0023014)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) MAPK cascade (GO:0000165)
p38MAPK cascade [Inferred is_a relation] is_a (inferred) stress-activated protein kinase signaling cascade (GO:0031098)
p38MAPK cascade [is_a relation] is_a  stress-activated MAPK cascade (GO:0051403)
Children of p38MAPK cascade (GO:0038066)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of p38MAPK cascade (GO:1903753) [negatively_regulates relation] negatively_regulates  p38MAPK cascade
positive regulation of p38MAPK cascade (GO:1900745) [positively_regulates relation] positively_regulates  p38MAPK cascade
regulation of p38MAPK cascade (GO:1900744) [regulates relation] regulates  p38MAPK cascade
None.