Term Information [More information on calcitriol biosynthetic process from calciol]

Accession
GO:0036378
Name
calcitriol biosynthetic process from calciol
Ontology
biological_process
Synonyms
calcitriol biosynthesis from calciol, vitamin D3 activation, 1alpha,25(OH)2D3 biosynthesis, 1alpha,25-dihydroxycholecalciferol biosynthesis, 1alpha,25-dihydroxyvitamin D3 biosynthesis
Definition
Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol. Source: GOC:rl, PMID:20511049, PMID:17426122, GOC:BHF
Comment
None
History
See term history for GO:0036378 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0036378 from QuickGO

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Ancestors of calcitriol biosynthetic process from calciol (GO:0036378)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
calcitriol biosynthetic process from calciol [is_a relation] is_a  biosynthetic process (GO:0009058)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) single-organism metabolic process (GO:0044710)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) single-organism biosynthetic process (GO:0044711)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) small molecule metabolic process (GO:0044281)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) cellular biosynthetic process (GO:0044249)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) lipid metabolic process (GO:0006629)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic hydroxy compound metabolic process (GO:1901615)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic substance biosynthetic process (GO:1901576)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) small molecule biosynthetic process (GO:0044283)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) vitamin metabolic process (GO:0006766)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) alcohol metabolic process (GO:0006066)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) fat-soluble vitamin metabolic process (GO:0006775)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) lipid biosynthetic process (GO:0008610)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic cyclic compound biosynthetic process (GO:1901362)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) organic hydroxy compound biosynthetic process (GO:1901617)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) steroid metabolic process (GO:0008202)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) vitamin biosynthetic process (GO:0009110)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) alcohol biosynthetic process (GO:0046165)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) cellular alcohol metabolic process (GO:0044107)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) fat-soluble vitamin biosynthetic process (GO:0042362)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) polyol metabolic process (GO:0019751)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) secondary alcohol metabolic process (GO:1902652)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) steroid biosynthetic process (GO:0006694)
calcitriol biosynthetic process from calciol [Inferred is_a relation] is_a (inferred) vitamin D metabolic process (GO:0042359)
calcitriol biosynthetic process from calciol [is_a relation] is_a  cellular alcohol biosynthetic process (GO:0044108)
calcitriol biosynthetic process from calciol [is_a relation] is_a  polyol biosynthetic process (GO:0046173)
calcitriol biosynthetic process from calciol [is_a relation] is_a  vitamin D biosynthetic process (GO:0042368)
calcitriol biosynthetic process from calciol [is_a relation] is_a  vitamin D3 metabolic process (GO:0070640)
Children of calcitriol biosynthetic process from calciol (GO:0036378)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
calcidiol 1-monooxygenase activity (GO:0004498) [part_of relation] part_of  calcitriol biosynthetic process from calciol
vitamin D3 25-hydroxylase activity (GO:0030343) [part_of relation] part_of  calcitriol biosynthetic process from calciol
None.