Term Information [More information on response to statin]

Accession
GO:0036273
Name
response to statin
Ontology
biological_process
Synonyms
response to HMG-CoA reductase inhibitor, response to hydroxymethylglutaryl-CoA reductase inhibitor
Definition
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. Source: GOC:hp
Comment
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
History
See term history for GO:0036273 at QuickGO
Subset
gocheck_do_not_manually_annotate
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0036273 from QuickGO

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Ancestors of response to statin (GO:0036273)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to statin [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
response to statin [is_a relation] is_a  response to stimulus (GO:0050896)
response to statin [Inferred is_a relation] is_a (inferred) response to chemical (GO:0042221)
response to statin [is_a relation] is_a  response to drug (GO:0042493)
response to statin [is_a relation] is_a  response to organic substance (GO:0010033)
response to statin [is_a relation] is_a  response to oxygen-containing compound (GO:1901700)
Children of response to statin (GO:0036273)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
response to simvastatin (GO:1903491) [is_a relation] is_a  response to statin
None.