Term Information [More information on SPOTS complex]

Accession
GO:0035339
Name
SPOTS complex
Ontology
cellular_component
Synonyms
serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex
Definition
A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis. Source: PMID:20182505
Comment
None
History
See term history for GO:0035339 at QuickGO
Subset
None
Community
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Feedback
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View this term in QuickGO.

Graph of GO:0035339 from QuickGO

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Ancestors of SPOTS complex (GO:0035339)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
SPOTS complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
SPOTS complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
SPOTS complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) molecular_function (GO:0003674)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) catalytic activity (GO:0003824)
SPOTS complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
SPOTS complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
SPOTS complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) transferase activity (GO:0016740)
SPOTS complex [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
SPOTS complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
SPOTS complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
SPOTS complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) transferase activity, transferring acyl groups (GO:0016746)
SPOTS complex [Inferred part_of relation] part_of (inferred) cytoplasmic part (GO:0044444)
SPOTS complex [Inferred part_of relation] part_of (inferred) endomembrane system (GO:0012505)
SPOTS complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
SPOTS complex [Inferred part_of relation] part_of (inferred) membrane (GO:0016020)
SPOTS complex [Inferred part_of relation] part_of (inferred) organelle part (GO:0044422)
SPOTS complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747)
SPOTS complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
SPOTS complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum (GO:0005783)
SPOTS complex [Inferred part_of relation] part_of (inferred) intracellular organelle part (GO:0044446)
SPOTS complex [Inferred part_of relation] part_of (inferred) organelle membrane (GO:0031090)
SPOTS complex [Inferred capable_of relation] capable_of (inferred) S-acyltransferase activity (GO:0016417)
SPOTS complex [Inferred part_of relation] part_of (inferred) bounding membrane of organelle (GO:0098588)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) C-acyltransferase activity (GO:0016408)
SPOTS complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum part (GO:0044432)
SPOTS complex [Inferred part_of relation] part_of (inferred) membrane part (GO:0044425)
SPOTS complex [Inferred part_of relation] part_of (inferred) nuclear outer membrane-endoplasmic reticulum membrane network (GO:0042175)
SPOTS complex [Inferred capable_of relation] capable_of (inferred) palmitoyltransferase activity (GO:0016409)
SPOTS complex [Inferred capable_of relation] capable_of (inferred) protein-cysteine S-acyltransferase activity (GO:0019707)
SPOTS complex [Inferred is_a relation] is_a (inferred) transferase complex (GO:1990234)
SPOTS complex [Inferred capable_of relation] capable_of (inferred) C-palmitoyltransferase activity (GO:0016454)
SPOTS complex [Inferred part_of relation] part_of (inferred) endoplasmic reticulum membrane (GO:0005789)
SPOTS complex [Inferred is_a relation] is_a (inferred) membrane protein complex (GO:0098796)
SPOTS complex [Inferred is_a relation] is_a (inferred) palmitoyltransferase complex (GO:0002178)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) protein-cysteine S-palmitoyltransferase activity (GO:0019706)
SPOTS complex [Inferred is_a relation] is_a (inferred) endoplasmic reticulum palmitoyltransferase complex (GO:0031211)
SPOTS complex [Inferred capable_of part of relation] capable_of part of (inferred) serine C-palmitoyltransferase activity (GO:0004758)
SPOTS complex [is_a relation] is_a  serine C-palmitoyltransferase complex (GO:0017059)

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