Term Information [More information on hippo signaling]

Accession
GO:0035329
Name
hippo signaling
Ontology
biological_process
Synonyms
hippo signal transduction, hippo signaling pathway, hippo signaling cascade, hippo signalling cascade, SWH pathway, Salvador-Warts-Hippo signaling pathway
Definition
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. Source: PMID:17318211, PMID:18328423
Comment
None
History
See term history for GO:0035329 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Contacting server...
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Graph of GO:0035329 from QuickGO

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Ancestors of hippo signaling (GO:0035329)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hippo signaling [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
hippo signaling [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
hippo signaling [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
hippo signaling [Inferred occurs_in relation] occurs_in (inferred) cellular_component (GO:0005575)
hippo signaling [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
hippo signaling [Inferred occurs_in relation] occurs_in (inferred) cell (GO:0005623)
hippo signaling [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
hippo signaling [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
hippo signaling [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
hippo signaling [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
hippo signaling [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
hippo signaling [Inferred occurs_in relation] occurs_in (inferred) cell part (GO:0044464)
hippo signaling [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
hippo signaling [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
hippo signaling [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
hippo signaling [Inferred occurs_in relation] occurs_in (inferred) intracellular (GO:0005622)
hippo signaling [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
hippo signaling [is_a relation] is_a  intracellular signal transduction (GO:0035556)
Children of hippo signaling (GO:0035329)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hippo signaling (GO:0035331) [negatively_regulates relation] negatively_regulates  hippo signaling
positive regulation of hippo signaling (GO:0035332) [positively_regulates relation] positively_regulates  hippo signaling
regulation of hippo signaling (GO:0035330) [regulates relation] regulates  hippo signaling
None.