Term Information [More information on mRNA cleavage involved in gene silencing by miRNA]

Accession
GO:0035279
Name
mRNA cleavage involved in gene silencing by miRNA
Ontology
biological_process
Synonyms
gene silencing by miRNA, mRNA cleavage, mRNA cleavage involved in gene silencing by microRNA, miRNA-mediated gene silencing, mRNA cleavage
Definition
The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. Source: GOC:dph, PMID:14744438, GOC:mtg_lung, PMID:15196554
Comment
None
History
See term history for GO:0035279 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0035279 from QuickGO

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Ancestors of mRNA cleavage involved in gene silencing by miRNA (GO:0035279)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) biological regulation (GO:0065007)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) biosynthetic process (GO:0009058)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of biological process (GO:0050789)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) cellular biosynthetic process (GO:0044249)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of biological process (GO:0048519)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of metabolic process (GO:0019222)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) cellular amide metabolic process (GO:0043603)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) cellular aromatic compound metabolic process (GO:0006725)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) cellular nitrogen compound biosynthetic process (GO:0044271)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) gene expression (GO:0010467)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) heterocycle metabolic process (GO:0046483)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of metabolic process (GO:0009892)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) organic substance biosynthetic process (GO:1901576)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) organonitrogen compound metabolic process (GO:1901564)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular process (GO:0050794)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of macromolecule metabolic process (GO:0060255)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) amide biosynthetic process (GO:0043604)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) macromolecule biosynthetic process (GO:0009059)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular process (GO:0048523)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of macromolecule metabolic process (GO:0010605)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) nucleobase-containing compound metabolic process (GO:0006139)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) organonitrogen compound biosynthetic process (GO:1901566)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) peptide metabolic process (GO:0006518)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) protein metabolic process (GO:0019538)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of biosynthetic process (GO:0009889)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular metabolic process (GO:0031323)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of gene expression (GO:0010468)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of primary metabolic process (GO:0080090)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) cellular macromolecule biosynthetic process (GO:0034645)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) cellular protein metabolic process (GO:0044267)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of biosynthetic process (GO:0009890)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular metabolic process (GO:0031324)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of gene expression (GO:0010629)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) nucleic acid metabolic process (GO:0090304)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) peptide biosynthetic process (GO:0043043)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular biosynthetic process (GO:0031326)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of macromolecule biosynthetic process (GO:0010556)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of nitrogen compound metabolic process (GO:0051171)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of protein metabolic process (GO:0051246)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) gene silencing (GO:0016458)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular biosynthetic process (GO:0031327)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of macromolecule biosynthetic process (GO:0010558)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of nitrogen compound metabolic process (GO:0051172)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of protein metabolic process (GO:0051248)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) nucleic acid phosphodiester bond hydrolysis (GO:0090305)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) posttranscriptional regulation of gene expression (GO:0010608)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular amide metabolic process (GO:0034248)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular macromolecule biosynthetic process (GO:2000112)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of cellular protein metabolic process (GO:0032268)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of gene expression, epigenetic (GO:0040029)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) RNA metabolic process (GO:0016070)
mRNA cleavage involved in gene silencing by miRNA [Inferred related_to relation] related_to (inferred) translation (GO:0006412)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) gene silencing by RNA (GO:0031047)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) mRNA metabolic process (GO:0016071)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular amide metabolic process (GO:0034249)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular macromolecule biosynthetic process (GO:2000113)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of cellular protein metabolic process (GO:0032269)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) posttranscriptional gene silencing (GO:0016441)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) regulation of translation (GO:0006417)
mRNA cleavage involved in gene silencing by miRNA [Inferred is_a relation] is_a (inferred) RNA phosphodiester bond hydrolysis (GO:0090501)
mRNA cleavage involved in gene silencing by miRNA [is_a relation] is_a  mRNA cleavage (GO:0006379)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) negative regulation of translation (GO:0017148)
mRNA cleavage involved in gene silencing by miRNA [Inferred part_of relation] part_of (inferred) posttranscriptional gene silencing by RNA (GO:0035194)
mRNA cleavage involved in gene silencing by miRNA [part_of relation] part_of  gene silencing by miRNA (GO:0035195)
mRNA cleavage involved in gene silencing by miRNA [is_a relation] is_a  mRNA cleavage involved in gene silencing (GO:0098795)
Children of mRNA cleavage involved in gene silencing by miRNA (GO:0035279)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
endoribonuclease activity, cleaving miRNA-paired mRNA (GO:0090624) [part_of relation] part_of  mRNA cleavage involved in gene silencing by miRNA
None.