Term Information [More information on PRC1 complex]

Accession
GO:0035102
Name
PRC1 complex
Ontology
cellular_component
Synonyms
Polycomb repressive complex 1
Definition
A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. Source: PMID:10412979, GOC:bf
Comment
In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.
History
See term history for GO:0035102 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0035102 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of PRC1 complex (GO:0035102)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule metabolic process (GO:0043170)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular macromolecule metabolic process (GO:0044260)
PRC1 complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule modification (GO:0043412)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) protein metabolic process (GO:0019538)
PRC1 complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein metabolic process (GO:0044267)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification process (GO:0036211)
PRC1 complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein modification process (GO:0006464)
PRC1 complex [Inferred capable_of relation] capable_of (inferred) molecular_function (GO:0003674)
PRC1 complex [Inferred capable_of relation] capable_of (inferred) catalytic activity (GO:0003824)
PRC1 complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation or removal (GO:0070647)
PRC1 complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
PRC1 complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
PRC1 complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation (GO:0032446)
PRC1 complex [Inferred capable_of relation] capable_of (inferred) transferase activity (GO:0016740)
PRC1 complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
PRC1 complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
PRC1 complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) protein ubiquitination (GO:0016567)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-like protein transferase activity (GO:0019787)
PRC1 complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
PRC1 complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
PRC1 complex [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
PRC1 complex [Inferred capable_of relation] capable_of (inferred) ubiquitin-like protein ligase activity (GO:0061659)
PRC1 complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-protein transferase activity (GO:0004842)
PRC1 complex [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
PRC1 complex [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
PRC1 complex [Inferred is_a relation] is_a (inferred) transferase complex (GO:1990234)
PRC1 complex [Inferred capable_of relation] capable_of (inferred) ubiquitin protein ligase activity (GO:0061630)
PRC1 complex [Inferred is_a relation] is_a (inferred) nuclear part (GO:0044428)
PRC1 complex [Inferred is_a relation] is_a (inferred) ubiquitin ligase complex (GO:0000151)
PRC1 complex [is_a relation] is_a  nuclear ubiquitin ligase complex (GO:0000152)
PRC1 complex [is_a relation] is_a  PcG protein complex (GO:0031519)

This term has no children.

None.