Term Information [More information on beta-amyloid formation]

Accession
GO:0034205
Name
beta-amyloid formation
Ontology
biological_process
Synonyms
beta-amyloid polypeptide formation from APP, beta-amyloid polypeptide formation from amyloid precursor protein
Definition
The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP). Source: GOC:mah
Comment
Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because beta-amyloid can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the beta-amyloid polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form beta-amyloid. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000).
History
See term history for GO:0034205 at QuickGO
Subset
None
Community
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Feedback
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Contacting server...
View this term in QuickGO.

Graph of GO:0034205 from QuickGO

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Ancestors of beta-amyloid formation (GO:0034205)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
beta-amyloid formation [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) cellular amide metabolic process (GO:0043603)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) organonitrogen compound metabolic process (GO:1901564)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) amyloid precursor protein metabolic process (GO:0042982)
beta-amyloid formation [Inferred is_a relation] is_a (inferred) peptide metabolic process (GO:0006518)
beta-amyloid formation [is_a relation] is_a  amyloid precursor protein catabolic process (GO:0042987)
beta-amyloid formation [is_a relation] is_a  beta-amyloid metabolic process (GO:0050435)
Children of beta-amyloid formation (GO:0034205)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of beta-amyloid formation (GO:1902430) [negatively_regulates relation] negatively_regulates  beta-amyloid formation
positive regulation of beta-amyloid formation (GO:1902004) [positively_regulates relation] positively_regulates  beta-amyloid formation
regulation of beta-amyloid formation (GO:1902003) [regulates relation] regulates  beta-amyloid formation
None.