Term Information [More information on TSC1-TSC2 complex]

Accession
GO:0033596
Name
TSC1-TSC2 complex
Ontology
cellular_component
Synonyms
tuberin-hamartin complex, tuberous sclerosis complex
Definition
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway. Source: PMID:10585443, PMID:9580671, PMID:17121544
Comment
None
History
See term history for GO:0033596 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0033596 from QuickGO

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Ancestors of TSC1-TSC2 complex (GO:0033596)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cytoplasmic part (GO:0044444)
TSC1-TSC2 complex [Inferred part_of relation] part_of (inferred) cytosol (GO:0005829)
TSC1-TSC2 complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
TSC1-TSC2 complex [is_a relation] is_a  cytosolic part (GO:0044445)
TSC1-TSC2 complex [is_a relation] is_a  protein complex (GO:0043234)

This term has no children.

None.