Term Information [More information on Elongator holoenzyme complex]

Accession
GO:0033588
Name
Elongator holoenzyme complex
Ontology
cellular_component
Synonyms
alt. id: GO:0033589
Elongator core complex
Definition
A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes. Source: PMID:11435442, GOC:bhm, GOC:jh, PMID:15769872, GOC:mah, PMID:11689709, PMID:18755837, GOC:vw, PMID:17018299, PMID:23165209
Comment
Despite its name, this complex is no longer thought to be directly involved in transcriptional elongation (PMID:23165209).
History
See term history for GO:0033588 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0033588 from QuickGO

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Ancestors of Elongator holoenzyme complex (GO:0033588)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) nitrogen compound metabolic process (GO:0006807)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular aromatic compound metabolic process (GO:0006725)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular nitrogen compound metabolic process (GO:0034641)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) heterocycle metabolic process (GO:0046483)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) organic cyclic compound metabolic process (GO:1901360)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule metabolic process (GO:0043170)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleobase-containing compound metabolic process (GO:0006139)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular macromolecule metabolic process (GO:0044260)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) nucleic acid metabolic process (GO:0090304)
Elongator holoenzyme complex [Inferred related_to relation] related_to (inferred) gene expression (GO:0010467)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) RNA metabolic process (GO:0016070)
Elongator holoenzyme complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) ncRNA metabolic process (GO:0034660)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) RNA processing (GO:0006396)
Elongator holoenzyme complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule modification (GO:0043412)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) ncRNA processing (GO:0034470)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) tRNA metabolic process (GO:0006399)
Elongator holoenzyme complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) RNA modification (GO:0009451)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) tRNA processing (GO:0008033)
Elongator holoenzyme complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
Elongator holoenzyme complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
Elongator holoenzyme complex [Inferred capable_of part of relation] capable_of part of (inferred) tRNA modification (GO:0006400)
Elongator holoenzyme complex [is_a relation] is_a  intracellular part (GO:0044424)
Elongator holoenzyme complex [is_a relation] is_a  protein complex (GO:0043234)
Elongator holoenzyme complex [capable_of part of relation] capable_of part of  tRNA wobble base modification (GO:0002097)

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