Term Information [More information on Weibel-Palade body]

Accession
GO:0033093
Name
Weibel-Palade body
Ontology
cellular_component
Synonyms
None
Definition
A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses. Source: PMID:11935287, PMID:16087708
Comment
None
History
See term history for GO:0033093 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0033093 from QuickGO

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Ancestors of Weibel-Palade body (GO:0033093)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) cellular component organization or biogenesis (GO:0071840)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) localization (GO:0051179)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) cellular component organization (GO:0016043)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) establishment of localization (GO:0051234)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) single-organism process (GO:0044699)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) membrane organization (GO:0061024)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) organelle (GO:0043226)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) single-organism cellular process (GO:0044763)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) single-organism localization (GO:1902578)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) transport (GO:0006810)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) membrane fusion (GO:0061025)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) membrane-bounded organelle (GO:0043227)
Weibel-Palade body [Inferred capable_of relation] capable_of (inferred) organelle organization (GO:0006996)
Weibel-Palade body [Inferred capable_of relation] capable_of (inferred) single-organism membrane organization (GO:0044802)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) single-organism transport (GO:0044765)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) cytoplasm (GO:0005737)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) organelle fusion (GO:0048284)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) secretion (GO:0046903)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) single-organism membrane fusion (GO:0044801)
Weibel-Palade body [Inferred capable_of relation] capable_of (inferred) single-organism organelle organization (GO:1902589)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) vesicle (GO:0031982)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) cytoplasmic part (GO:0044444)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) intracellular organelle (GO:0043229)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) intracellular vesicle (GO:0097708)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) organelle membrane fusion (GO:0090174)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) secretion by cell (GO:0032940)
Weibel-Palade body [Inferred capable_of relation] capable_of (inferred) vesicle organization (GO:0016050)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) vesicle-mediated transport (GO:0016192)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) cytoplasmic vesicle (GO:0031410)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) exocytosis (GO:0006887)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) intracellular membrane-bounded organelle (GO:0043231)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) membrane-bounded vesicle (GO:0031988)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) plasma membrane fusion (GO:0045026)
Weibel-Palade body [Inferred capable_of part of relation] capable_of part of (inferred) vesicle fusion (GO:0006906)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) cytoplasmic, membrane-bounded vesicle (GO:0016023)
Weibel-Palade body [Inferred capable_of relation] capable_of (inferred) vesicle fusion to plasma membrane (GO:0099500)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) coated vesicle (GO:0030135)
Weibel-Palade body [Inferred part_of relation] part_of (inferred) endomembrane system (GO:0012505)
Weibel-Palade body [Inferred is_a relation] is_a (inferred) secretory vesicle (GO:0099503)
Weibel-Palade body [is_a relation] is_a  clathrin-coated vesicle (GO:0030136)
Weibel-Palade body [is_a relation] is_a  secretory granule (GO:0030141)

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Wikipedia
Weibel-Palade_body