AmiGO 2: Term Details for "receptor internalization" (GO:0031623)

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Term Information

Accession: GO:0031623
Name: receptor internalization
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. Source: PMID:19643732, GOC:signaling, GOC:bf, PMID:15006537, GOC:mah
Comment: None
History: See term history for GO:0031623 at QuickGO
Subset: None
Related: Link to all genes and gene products annotated to receptor internalization.; Link to all direct and indirect annotations to receptor internalization.; Link to all direct and indirect annotations download (limited to first 10,000) for receptor internalization.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0071704 organic substance metabolic process
GO:0006810 transport
GO:0044237 cellular metabolic process
GO:0043170 macromolecule metabolic process
GO:0044699 single-organism process
GO:0016192 vesicle-mediated transport
GO:0044260 cellular macromolecule metabolic process
GO:0006897 endocytosis
GO:1902578 single-organism localization
GO:0043112 receptor metabolic process
GO:0006898 receptor-mediated endocytosis
GO:0044763 single-organism cellular process
GO:0044710 single-organism metabolic process
GO:0044765 single-organism transport
GO:0031623 receptor internalization
GO:0036300 B cell receptor internalization
GO:0002031 G-protein coupled receptor internalization
GO:0038016 insulin receptor internalization
GO:0002091 negative regulation of receptor internalization
GO:0038011 negative regulation of signal transduction by receptor internalization
GO:0099590 neurotransmitter receptor internalization
GO:0002092 positive regulation of receptor internalization
GO:0038010 positive regulation of signal transduction by receptor internalization
GO:0098884 postsynaptic neurotransmitter receptor internalization
GO:2000286 receptor internalization involved in canonical Wnt signaling pathway
GO:0002090 regulation of receptor internalization
GO:0038009 regulation of signal transduction by receptor internalization
GO:0038017 Wnt receptor internalization

Parents of receptor internalization (GO:0031623)

subject	relation	object
receptor internalization	is_a	receptor-mediated endocytosis (GO:0006898)
receptor internalization	is_a	single-organism transport (GO:0044765)
receptor internalization	is_a	receptor metabolic process (GO:0043112)
receptor internalization	is_a	single-organism metabolic process (GO:0044710)
receptor internalization	is_a	single-organism cellular process (GO:0044763)

Children of receptor internalization (GO:0031623)

subject	relation	object
regulation of receptor internalization (GO:0002090)	regulates	receptor internalization
G-protein coupled receptor internalization (GO:0002031)	is_a	receptor internalization
postsynaptic neurotransmitter receptor internalization (GO:0098884)	is_a	receptor internalization
neurotransmitter receptor internalization (GO:0099590)	is_a	receptor internalization
insulin receptor internalization (GO:0038016)	is_a	receptor internalization
Wnt receptor internalization (GO:0038017)	is_a	receptor internalization
negative regulation of signal transduction by receptor internalization (GO:0038011)	is_a	receptor internalization
receptor internalization involved in canonical Wnt signaling pathway (GO:2000286)	is_a	receptor internalization
regulation of signal transduction by receptor internalization (GO:0038009)	is_a	receptor internalization
B cell receptor internalization (GO:0036300)	is_a	receptor internalization
negative regulation of receptor internalization (GO:0002091)	negatively_regulates	receptor internalization
positive regulation of signal transduction by receptor internalization (GO:0038010)	is_a	receptor internalization
positive regulation of receptor internalization (GO:0002092)	positively_regulates	receptor internalization

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