Term Information [More information on Mre11 complex]

Accession
GO:0030870
Name
Mre11 complex
Ontology
cellular_component
Synonyms
MRN complex, MRX complex, RAD50-MRE11-NBN complex, RMX complex, Rad50 complex, Rad50-Rad32-Nbs1 complex
Definition
Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. Source: PMID:11988766, PMID:17674145, GOC:mah, GOC:vw
Comment
None
History
See term history for GO:0030870 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0030870 from QuickGO

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Ancestors of Mre11 complex (GO:0030870)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Mre11 complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
Mre11 complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
Mre11 complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
Mre11 complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
Mre11 complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
Mre11 complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
Mre11 complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
Mre11 complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
Mre11 complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
Mre11 complex [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
Mre11 complex [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
Mre11 complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
Mre11 complex [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
Mre11 complex [is_a relation] is_a  nuclear part (GO:0044428)
Mre11 complex [is_a relation] is_a  protein complex (GO:0043234)

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