Term Information [More information on ER-associated ubiquitin-dependent protein catabolic process]

Accession
GO:0030433
Name
ER-associated ubiquitin-dependent protein catabolic process
Ontology
biological_process
Synonyms
ER-associated protein breakdown, ER-associated protein catabolic process, ER-associated protein catabolism, ER-associated protein degradation, endoplasmic reticulum-associated protein catabolic process, endoplasmic reticulum-associated protein catabolism, proteasomal protein catabolism of ER proteins, ERAD
Definition
The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Source: GOC:rb, GOC:mah, PMID:14607247, PMID:19520858
Comment
See also the biological process terms 'ERAD pathway ; GO:0036503', 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
History
See term history for GO:0030433 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0030433 from QuickGO

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Ancestors of ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) catabolic process (GO:0009056)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) organic substance catabolic process (GO:1901575)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular catabolic process (GO:0044248)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular macromolecule metabolic process (GO:0044260)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) macromolecule catabolic process (GO:0009057)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular macromolecule catabolic process (GO:0044265)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular protein metabolic process (GO:0044267)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) protein catabolic process (GO:0030163)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular protein catabolic process (GO:0044257)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) proteolysis (GO:0006508)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) modification-dependent macromolecule catabolic process (GO:0043632)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) proteolysis involved in cellular protein catabolic process (GO:0051603)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) response to stress (GO:0006950)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) cellular response to stress (GO:0033554)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) modification-dependent protein catabolic process (GO:0019941)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) proteasomal protein catabolic process (GO:0010498)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) response to endoplasmic reticulum stress (GO:0034976)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) response to organic substance (GO:0010033)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) single-organism catabolic process (GO:0044712)
ER-associated ubiquitin-dependent protein catabolic process [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
ER-associated ubiquitin-dependent protein catabolic process [Inferred is_a relation] is_a (inferred) ubiquitin-dependent protein catabolic process (GO:0006511)
ER-associated ubiquitin-dependent protein catabolic process [part_of relation] part_of  ERAD pathway (GO:0036503)
ER-associated ubiquitin-dependent protein catabolic process [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
Children of ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ER-associated misfolded protein catabolic process (GO:0071712) [is_a relation] is_a  ER-associated ubiquitin-dependent protein catabolic process
negative regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903070) [negatively_regulates relation] negatively_regulates  ER-associated ubiquitin-dependent protein catabolic process
positive regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903071) [positively_regulates relation] positively_regulates  ER-associated ubiquitin-dependent protein catabolic process
regulation of ER-associated ubiquitin-dependent protein catabolic process (GO:1903069) [regulates relation] regulates  ER-associated ubiquitin-dependent protein catabolic process
None.