AmiGO 2: Term Details for "translesion synthesis" (GO:0019985)

Term Information

Accession: GO:0019985
Name: translesion synthesis
Ontology: biological_process
Synonyms: bypass DNA synthesis
Alternate IDs: None
Definition: The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. Source: GOC:vw, GOC:elh, PMID:10535901
Comment: None
History: See term history for GO:0019985 at QuickGO
Subset: gosubset_prok
Related: Link to all genes and gene products annotated to translesion synthesis.; Link to all direct and indirect annotations to translesion synthesis.; Link to all direct and indirect annotations download (limited to first 10,000) for translesion synthesis.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0044237 cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0009058 biosynthetic process
GO:0006725 cellular aromatic compound metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0046483 heterocycle metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:0044238 primary metabolic process
GO:0050896 response to stimulus
GO:0044249 cellular biosynthetic process
GO:0051716 cellular response to stimulus
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0006950 response to stress
GO:0019438 aromatic compound biosynthetic process
GO:0044260 cellular macromolecule metabolic process
GO:0044271 cellular nitrogen compound biosynthetic process
GO:0033554 cellular response to stress
GO:0018130 heterocycle biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0034645 cellular macromolecule biosynthetic process
GO:0006974 cellular response to DNA damage stimulus
GO:0006259 DNA metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0071897 DNA biosynthetic process
GO:0006281 DNA repair
GO:0000731 DNA synthesis involved in DNA repair
GO:0006301 postreplication repair
GO:0019985 translesion synthesis
GO:0070987 error-free translesion synthesis
GO:0042276 error-prone translesion synthesis

Parents of translesion synthesis (GO:0019985)

subject	relation	object
translesion synthesis	is_a	DNA synthesis involved in DNA repair (GO:0000731)
translesion synthesis	is_a	postreplication repair (GO:0006301)

Children of translesion synthesis (GO:0019985)

subject	relation	object
error-prone translesion synthesis (GO:0042276)	is_a	translesion synthesis
error-free translesion synthesis (GO:0070987)	is_a	translesion synthesis

Reactome: REACT_115864; REACT_115941; REACT_116052; REACT_116049; REACT_115598; REACT_115640