Term Information [More information on SCF ubiquitin ligase complex]

Accession
GO:0019005
Name
SCF ubiquitin ligase complex
Ontology
cellular_component
Synonyms
CDL1 complex, CRL1 complex, Cul1-RING ubiquitin ligase complex, SCF complex, Skp1/Cul1/F-box protein complex, cullin-RING ligase 1, SCF complex substrate recognition subunit
Definition
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Source: PMID:15688063, PMID:15571813
Comment
None
History
See term history for GO:0019005 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0019005 from QuickGO

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Ancestors of SCF ubiquitin ligase complex (GO:0019005)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule metabolic process (GO:0043170)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular macromolecule metabolic process (GO:0044260)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule modification (GO:0043412)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) protein metabolic process (GO:0019538)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein metabolic process (GO:0044267)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification process (GO:0036211)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein modification process (GO:0006464)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) molecular_function (GO:0003674)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) catalytic activity (GO:0003824)
SCF ubiquitin ligase complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation or removal (GO:0070647)
SCF ubiquitin ligase complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation (GO:0032446)
SCF ubiquitin ligase complex [Inferred capable_of relation] capable_of (inferred) transferase activity (GO:0016740)
SCF ubiquitin ligase complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) protein ubiquitination (GO:0016567)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-like protein transferase activity (GO:0019787)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
SCF ubiquitin ligase complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
SCF ubiquitin ligase complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-like protein ligase activity (GO:0061659)
SCF ubiquitin ligase complex [Inferred capable_of relation] capable_of (inferred) ubiquitin-protein transferase activity (GO:0004842)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) intracellular part (GO:0044424)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) transferase complex (GO:1990234)
SCF ubiquitin ligase complex [Inferred capable_of relation] capable_of (inferred) ubiquitin protein ligase activity (GO:0061630)
SCF ubiquitin ligase complex [Inferred is_a relation] is_a (inferred) ubiquitin ligase complex (GO:0000151)
SCF ubiquitin ligase complex [is_a relation] is_a  cullin-RING ubiquitin ligase complex (GO:0031461)
Children of SCF ubiquitin ligase complex (GO:0019005)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoplasmic SCF ubiquitin ligase complex (GO:0043223) [is_a relation] is_a  SCF ubiquitin ligase complex
nuclear SCF ubiquitin ligase complex (GO:0043224) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Cdc4 ubiquitin ligase complex (GO:0097660) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Ctf13 ubiquitin ligase complex (GO:0097661) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Das1 ubiquitin ligase complex (GO:0097662) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Dia2/Pof3 ubiquitin ligase complex (GO:0097663) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Grr1/Pof2 ubiquitin ligase complex (GO:0097664) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Hrt3/Pof7 ubiquitin ligase complex (GO:0097675) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Mdm30 ubiquitin ligase complex (GO:0097665) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Met30/Pof1 ubiquitin ligase complex (GO:0097666) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Pof5 ubiquitin ligase complex (GO:0097672) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Rcy1/Pof6 ubiquitin ligase complex (GO:0097667) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Saf1/Pof9 ubiquitin ligase complex (GO:0097668) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Skp2 ubiquitin ligase complex (GO:0097669) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Ucc1 ubiquitin ligase complex (GO:0097673) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-Ufo1/Pof10 ubiquitin ligase complex (GO:0097670) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-YDR131C ubiquitin ligase complex (GO:0097671) [is_a relation] is_a  SCF ubiquitin ligase complex
SCF-YLR352W ubiquitin ligase complex (GO:0097674) [is_a relation] is_a  SCF ubiquitin ligase complex
Wikipedia
SCF_complex