Term Information [More information on phospholipid scrambling]

Accession
GO:0017121
Name
phospholipid scrambling
Ontology
biological_process
Synonyms
PL scrambling
Definition
The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). Source: PMID:20043909, GOC:cjm, PMID:20302864
Comment
Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.
History
See term history for GO:0017121 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0017121 from QuickGO

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Ancestors of phospholipid scrambling (GO:0017121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phospholipid scrambling [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
phospholipid scrambling [Inferred part_of relation] part_of (inferred) cellular component organization or biogenesis (GO:0071840)
phospholipid scrambling [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
phospholipid scrambling [Inferred part_of relation] part_of (inferred) cellular component organization (GO:0016043)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
phospholipid scrambling [Inferred regulates relation] regulates (inferred) biological attribute (OBA:0000001)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) membrane organization (GO:0061024)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
phospholipid scrambling [Inferred part_of relation] part_of (inferred) endomembrane system organization (GO:0010256)
phospholipid scrambling [Inferred regulates relation] regulates (inferred) membrane lipid distribution (OBA:0000098)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) regulation of biological quality (GO:0065008)
phospholipid scrambling [Inferred is_a relation] is_a (inferred) single-organism membrane organization (GO:0044802)
phospholipid scrambling [is_a relation] is_a  plasma membrane organization (GO:0007009)
phospholipid scrambling [is_a relation] is_a  regulation of membrane lipid distribution (GO:0097035)
Children of phospholipid scrambling (GO:0017121)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
calcium activated phospholipid scrambling (GO:0061588) [is_a relation] is_a  phospholipid scrambling
phosphatidylserine exposure on apoptotic cell surface (GO:0070782) [is_a relation] is_a  phospholipid scrambling
phosphatidylserine exposure on blood platelet (GO:0097045) [is_a relation] is_a  phospholipid scrambling
phosphatidylserine exposure on osteoblast involved in bone mineralization (GO:0061592) [is_a relation] is_a  phospholipid scrambling
phospholipid scramblase activity (GO:0017128) [part_of relation] part_of  phospholipid scrambling
None.