Term Information [More information on NuRD complex]

Accession
GO:0016581
Name
NuRD complex
Ontology
cellular_component
Synonyms
Mi-2 complex, NRD complex, nucleosome remodeling and histone deacetylation complex
Definition
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. Source: PMID:11743021, PMID:10589671, PMID:17289569
Comment
None
History
See term history for GO:0016581 at QuickGO
Subset
None
Community
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Graph of GO:0016581 from QuickGO

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Ancestors of NuRD complex (GO:0016581)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NuRD complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
NuRD complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
NuRD complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular component organization or biogenesis (GO:0071840)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular component organization (GO:0016043)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule metabolic process (GO:0043170)
NuRD complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) organelle organization (GO:0006996)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular macromolecule metabolic process (GO:0044260)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) chromosome organization (GO:0051276)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecular complex subunit organization (GO:0043933)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule modification (GO:0043412)
NuRD complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) protein metabolic process (GO:0019538)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein metabolic process (GO:0044267)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) chromatin organization (GO:0006325)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
NuRD complex [Inferred part_of relation] part_of (inferred) membrane-enclosed lumen (GO:0031974)
NuRD complex [Inferred capable_of relation] capable_of (inferred) molecular_function (GO:0003674)
NuRD complex [Inferred part_of relation] part_of (inferred) organelle part (GO:0044422)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification process (GO:0036211)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism process (GO:0044699)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) catalytic activity (GO:0003824)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein modification process (GO:0006464)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) chromatin modification (GO:0016568)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular organelle part (GO:0044446)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule deacylation (GO:0098732)
NuRD complex [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
NuRD complex [Inferred part_of relation] part_of (inferred) organelle lumen (GO:0043233)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism cellular process (GO:0044763)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) covalent chromatin modification (GO:0016569)
NuRD complex [Inferred capable_of relation] capable_of (inferred) hydrolase activity (GO:0016787)
NuRD complex [Inferred part_of relation] part_of (inferred) intracellular organelle lumen (GO:0070013)
NuRD complex [Inferred part_of relation] part_of (inferred) nuclear part (GO:0044428)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) protein deacylation (GO:0035601)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism metabolic process (GO:0044710)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism organelle organization (GO:1902589)
NuRD complex [Inferred capable_of relation] capable_of (inferred) deacetylase activity (GO:0019213)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) histone modification (GO:0016570)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810)
NuRD complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
NuRD complex [Inferred part_of relation] part_of (inferred) nuclear lumen (GO:0031981)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) protein deacetylation (GO:0006476)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) histone deacetylation (GO:0016575)
NuRD complex [Inferred capable_of relation] capable_of (inferred) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
NuRD complex [Inferred part_of relation] part_of (inferred) nucleoplasm (GO:0005654)
NuRD complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
NuRD complex [Inferred capable_of relation] capable_of (inferred) protein deacetylase activity (GO:0033558)
NuRD complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
NuRD complex [Inferred capable_of part of relation] capable_of part of (inferred) histone deacetylase activity (GO:0004407)
NuRD complex [Inferred is_a relation] is_a (inferred) nucleoplasm part (GO:0044451)
NuRD complex [Inferred is_a relation] is_a (inferred) SWI/SNF superfamily-type complex (GO:0070603)
NuRD complex [Inferred is_a relation] is_a (inferred) transcriptional repressor complex (GO:0017053)
NuRD complex [is_a relation] is_a  CHD-type complex (GO:0090545)
NuRD complex [is_a relation] is_a  histone deacetylase complex (GO:0000118)
NuRD complex [is_a relation] is_a  nuclear transcriptional repressor complex (GO:0090568)

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