Term Information [More information on RISC complex]

Accession
GO:0016442
Name
RISC complex
Ontology
cellular_component
Synonyms
RNA-induced silencing complex
Definition
A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. Source: PMID:10749213, PMID:15145345
Comment
None
History
See term history for GO:0016442 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0016442 from QuickGO

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Ancestors of RISC complex (GO:0016442)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RISC complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
RISC complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
RISC complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
RISC complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
RISC complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
RISC complex [Inferred is_a relation] is_a (inferred) intracellular part (GO:0044424)
RISC complex [Inferred is_a relation] is_a (inferred) ribonucleoprotein complex (GO:1990904)
RISC complex [Inferred is_a relation] is_a (inferred) intracellular ribonucleoprotein complex (GO:0030529)
RISC complex [is_a relation] is_a  RNAi effector complex (GO:0031332)

This term has no children.