Term Information [More information on prefoldin complex]

Accession
GO:0016272
Name
prefoldin complex
Ontology
cellular_component
Synonyms
GIM complex
Definition
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. Source: PMID:24068951, PMID:9630229, GOC:jl, PMID:17384227
Comment
None
History
See term history for GO:0016272 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0016272 from QuickGO

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Ancestors of prefoldin complex (GO:0016272)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
prefoldin complex [Inferred is_a relation] is_a (inferred) cellular_component (GO:0005575)
prefoldin complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
prefoldin complex [is_a relation] is_a  protein complex (GO:0043234)

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Wikipedia
Prefoldin