Term Information [More information on programmed cell death]

Accession
GO:0012501
Name
programmed cell death
Ontology
biological_process
Synonyms
alt. id: GO:0016244
PCD, RCD, caspase-independent apoptosis, caspase-independent cell death, non-apoptotic programmed cell death, nonapoptotic programmed cell death, regulated cell death
Definition
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. Source: GOC:mtg_apoptosis, GOC:lr
Comment
Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children, which are descendants of GO:0034050 'host programmed cell death induced by symbiont'.
History
See term history for GO:0012501 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0012501 from QuickGO

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Ancestors of programmed cell death (GO:0012501)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
programmed cell death [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
programmed cell death [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
programmed cell death [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
programmed cell death [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
programmed cell death [is_a relation] is_a  cell death (GO:0008219)
Children of programmed cell death (GO:0012501)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
apoptotic process (GO:0006915) [is_a relation] is_a  programmed cell death
autophagic cell death (GO:0048102) [is_a relation] is_a  programmed cell death
cornification (GO:0070268) [is_a relation] is_a  programmed cell death
death receptor activity (GO:0005035) [part_of relation] part_of  programmed cell death
developmental programmed cell death (GO:0010623) [is_a relation] is_a  programmed cell death
ectopic germ cell programmed cell death (GO:0035234) [is_a relation] is_a  programmed cell death
ferroptosis (GO:0097707) [is_a relation] is_a  programmed cell death
host programmed cell death induced by symbiont (GO:0034050) [is_a relation] is_a  programmed cell death
mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) [part_of relation] part_of  programmed cell death
negative regulation of programmed cell death (GO:0043069) [negatively_regulates relation] negatively_regulates  programmed cell death
positive regulation of programmed cell death (GO:0043068) [positively_regulates relation] positively_regulates  programmed cell death
programmed cell death in response to reactive oxygen species (GO:0097468) [is_a relation] is_a  programmed cell death
programmed necrotic cell death (GO:0097300) [is_a relation] is_a  programmed cell death
pyroptosis (GO:0070269) [is_a relation] is_a  programmed cell death
regulation of programmed cell death (GO:0043067) [regulates relation] regulates  programmed cell death