Term Information [More information on granzyme-mediated apoptotic signaling pathway]

Accession
GO:0008626
Name
granzyme-mediated apoptotic signaling pathway
Ontology
biological_process
Synonyms
apoptotic signaling pathway in response to granzyme, induction of apoptosis by granzyme
Definition
A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells. Source: PMID:17158907, GOC:mtg_apoptosis
Comment
None
History
See term history for GO:0008626 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0008626 from QuickGO

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Ancestors of granzyme-mediated apoptotic signaling pathway (GO:0008626)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
granzyme-mediated apoptotic signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
granzyme-mediated apoptotic signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
granzyme-mediated apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) death (GO:0016265)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell death (GO:0008219)
granzyme-mediated apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) programmed cell death (GO:0012501)
granzyme-mediated apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
granzyme-mediated apoptotic signaling pathway [Inferred part_of relation] part_of (inferred) apoptotic process (GO:0006915)
granzyme-mediated apoptotic signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
granzyme-mediated apoptotic signaling pathway [is_a relation] is_a  apoptotic signaling pathway (GO:0097190)

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