Term Information [More information on cholesterol monooxygenase (side-chain-cleaving) activity]

Accession
GO:0008386
Name
cholesterol monooxygenase (side-chain-cleaving) activity
Ontology
molecular_function
Synonyms
cholesterol 20-22-desmolase activity, cholesterol C(20-22) desmolase activity, cholesterol C20-22 desmolase activity, cholesterol desmolase activity, cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving), desmolase, steroid 20-22, C27-side chain cleavage enzyme, cholesterol side-chain cleavage enzyme activity, cholesterol side-chain-cleaving enzyme activity, cytochrome P-450scc, cytochrome p450scc, enzymes, cholesterol side-chain-cleaving, Cyp11a1, cytochrome P-450(scc) activity, cytochrome p450(scc) activity, steroid 20-22 desmolase activity, steroid 20-22-lyase activity
Definition
Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O. Source: EC:1.14.15.6
Comment
None
History
See term history for GO:0008386 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0008386 from QuickGO

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Ancestors of cholesterol monooxygenase (side-chain-cleaving) activity (GO:0008386)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred is_a relation] is_a (inferred) monooxygenase activity (GO:0004497)
cholesterol monooxygenase (side-chain-cleaving) activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
cholesterol monooxygenase (side-chain-cleaving) activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (GO:0016713)
cholesterol monooxygenase (side-chain-cleaving) activity [is_a relation] is_a  steroid hydroxylase activity (GO:0008395)

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