Term Information [More information on metallopeptidase activity]

Accession
GO:0008237
Name
metallopeptidase activity
Ontology
molecular_function
Synonyms
metalloprotease activity, metalloproteinase activity
Definition
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Source: GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE
Comment
None
History
See term history for GO:0008237 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0008237 from QuickGO

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Ancestors of metallopeptidase activity (GO:0008237)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
metallopeptidase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
metallopeptidase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
metallopeptidase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
metallopeptidase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
metallopeptidase activity [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
metallopeptidase activity [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
metallopeptidase activity [is_a relation] is_a  peptidase activity, acting on L-amino acid peptides (GO:0070011)
Children of metallopeptidase activity (GO:0008237)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
H-gal-GP complex (GO:1990850) [capable_of relation] capable_of  metallopeptidase activity
metalloendopeptidase activity (GO:0004222) [is_a relation] is_a  metallopeptidase activity
metalloexopeptidase activity (GO:0008235) [is_a relation] is_a  metallopeptidase activity
negative regulation of metallopeptidase activity (GO:1905049) [negatively_regulates relation] negatively_regulates  metallopeptidase activity
positive regulation of metallopeptidase activity (GO:1905050) [positively_regulates relation] positively_regulates  metallopeptidase activity
regulation of metallopeptidase activity (GO:1905048) [regulates relation] regulates  metallopeptidase activity