Term Information [More information on COP9 signalosome]

Accession
GO:0008180
Name
COP9 signalosome
Ontology
cellular_component
Synonyms
COP9 complex, CSN, signalosome
Definition
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. Source: PMID:14570571, PMID:11019806, PMID:12186635
Comment
None
History
See term history for GO:0008180 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0008180 from QuickGO

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Ancestors of COP9 signalosome (GO:0008180)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
COP9 signalosome [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
COP9 signalosome [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
COP9 signalosome [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
COP9 signalosome [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
COP9 signalosome [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
COP9 signalosome [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
COP9 signalosome [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
COP9 signalosome [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
COP9 signalosome [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
COP9 signalosome [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
COP9 signalosome [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
COP9 signalosome [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
COP9 signalosome [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
COP9 signalosome [is_a relation] is_a  nuclear part (GO:0044428)
COP9 signalosome [is_a relation] is_a  protein complex (GO:0043234)

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