Term Information [More information on cholesterol 7-alpha-monooxygenase activity]

Accession
GO:0008123
Name
cholesterol 7-alpha-monooxygenase activity
Ontology
molecular_function
Synonyms
cholesterol 7-alpha-hydroxylase activity, cholesterol 7alpha-hydroxylase activity, cholesterol 7alpha-monooxygenase activity, cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating), cytochrome P450 CYP7A1
Definition
Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O. Source: EC:1.14.13.17
Comment
None
History
See term history for GO:0008123 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0008123 from QuickGO

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Ancestors of cholesterol 7-alpha-monooxygenase activity (GO:0008123)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cholesterol 7-alpha-monooxygenase activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
cholesterol 7-alpha-monooxygenase activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
cholesterol 7-alpha-monooxygenase activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
cholesterol 7-alpha-monooxygenase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
cholesterol 7-alpha-monooxygenase activity [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
cholesterol 7-alpha-monooxygenase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
cholesterol 7-alpha-monooxygenase activity [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
cholesterol 7-alpha-monooxygenase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity (GO:0016491)
cholesterol 7-alpha-monooxygenase activity [Inferred is_a relation] is_a (inferred) monooxygenase activity (GO:0004497)
cholesterol 7-alpha-monooxygenase activity [Inferred is_a relation] is_a (inferred) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)
cholesterol 7-alpha-monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)
cholesterol 7-alpha-monooxygenase activity [is_a relation] is_a  steroid hydroxylase activity (GO:0008395)

This term has no children.