Term Information [More information on chemokine activity]

Accession
GO:0008009
Name
chemokine activity
Ontology
molecular_function
Synonyms
None
Definition
The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. Source: GOC:rl, PMID:12183377, http://en.wikipedia.org/wiki/Chemokine, GOC:BHF, http://www.copewithcytokines.de/cope.cgi?key=Cytokines
Comment
See also the molecular function term 'cytokine activity ; GO:0005125'.
History
See term history for GO:0008009 at QuickGO
Subset
goslim_chembl
Community
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Feedback
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Contacting server...
View this term in QuickGO.

Graph of GO:0008009 from QuickGO

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Ancestors of chemokine activity (GO:0008009)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chemokine activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
chemokine activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
chemokine activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
chemokine activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
chemokine activity [Inferred is_a relation] is_a (inferred) binding (GO:0005488)
chemokine activity [Inferred part_of relation] part_of (inferred) localization (GO:0051179)
chemokine activity [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
chemokine activity [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
chemokine activity [Inferred part_of relation] part_of (inferred) localization of cell (GO:0051674)
chemokine activity [Inferred part_of relation] part_of (inferred) locomotion (GO:0040011)
chemokine activity [Inferred part_of relation] part_of (inferred) movement of cell or subcellular component (GO:0006928)
chemokine activity [Inferred is_a relation] is_a (inferred) protein binding (GO:0005515)
chemokine activity [Inferred part_of relation] part_of (inferred) response to external stimulus (GO:0009605)
chemokine activity [Inferred part_of relation] part_of (inferred) cell motility (GO:0048870)
chemokine activity [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
chemokine activity [Inferred is_a relation] is_a (inferred) receptor binding (GO:0005102)
chemokine activity [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
chemokine activity [Inferred part_of relation] part_of (inferred) taxis (GO:0042330)
chemokine activity [Inferred part_of relation] part_of (inferred) cell migration (GO:0016477)
chemokine activity [Inferred part_of relation] part_of (inferred) cellular response to chemical stimulus (GO:0070887)
chemokine activity [Inferred part_of relation] part_of (inferred) chemotaxis (GO:0006935)
chemokine activity [Inferred is_a relation] is_a (inferred) cytokine receptor binding (GO:0005126)
chemokine activity [Inferred is_a relation] is_a (inferred) G-protein coupled receptor binding (GO:0001664)
chemokine activity [part_of relation] part_of  cell chemotaxis (GO:0060326)
chemokine activity [is_a relation] is_a  chemokine receptor binding (GO:0042379)
chemokine activity [is_a relation] is_a  cytokine activity (GO:0005125)
Children of chemokine activity (GO:0008009)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of chemokine activity (GO:1900137) [negatively_regulates relation] negatively_regulates  chemokine activity
regulation of chemokine activity (GO:1900136) [regulates relation] regulates  chemokine activity
None.