Term Information [More information on epidermal growth factor receptor signaling pathway]

Accession
GO:0007173
Name
epidermal growth factor receptor signaling pathway
Ontology
biological_process
Synonyms
EGF receptor signaling pathway, EGF receptor signalling pathway, EGFR signaling pathway, ERBB1 signaling pathway, epidermal growth factor receptor signalling pathway, receptor tyrosine-protein kinase erbB-1 signaling pathway
Definition
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. Source: GOC:ceb, PR:000006933
Comment
None
History
See term history for GO:0007173 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0007173 from QuickGO

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Ancestors of epidermal growth factor receptor signaling pathway (GO:0007173)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epidermal growth factor receptor signaling pathway [Inferred regulates relation] regulates (inferred) biological_process (GO:0008150)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
epidermal growth factor receptor signaling pathway [Inferred regulates relation] regulates (inferred) cellular process (GO:0009987)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) regulation of cellular process (GO:0050794)
epidermal growth factor receptor signaling pathway [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) signal transduction (GO:0007165)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) cell surface receptor signaling pathway (GO:0007166)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) enzyme linked receptor protein signaling pathway (GO:0007167)
epidermal growth factor receptor signaling pathway [Inferred is_a relation] is_a (inferred) transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)
epidermal growth factor receptor signaling pathway [is_a relation] is_a  ERBB signaling pathway (GO:0038127)
Children of epidermal growth factor receptor signaling pathway (GO:0007173)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
coreceptor activity involved in epidermal growth factor receptor signaling pathway (GO:0060724) [part_of relation] part_of  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway involved in lung development (GO:0060507) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway via MAPK cascade (GO:0038029) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity (GO:0038167) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor signaling pathway involved in forebrain neuron fate commitment (GO:0022026) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
epidermal growth factor-activated receptor activity (GO:0005006) [part_of relation] part_of  epidermal growth factor receptor signaling pathway
ERBB2-EGFR signaling pathway (GO:0038134) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
ERBB4-EGFR signaling pathway (GO:0038137) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
gurken signaling pathway (GO:0008314) [is_a relation] is_a  epidermal growth factor receptor signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway (GO:0042059) [negatively_regulates relation] negatively_regulates  epidermal growth factor receptor signaling pathway
positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) [positively_regulates relation] positively_regulates  epidermal growth factor receptor signaling pathway
regulation of epidermal growth factor receptor signaling pathway (GO:0042058) [regulates relation] regulates  epidermal growth factor receptor signaling pathway