Term Information [More information on complement activation]

Accession
GO:0006956
Name
complement activation
Ontology
biological_process
Synonyms
complement cascade, complement response, complement activity
Definition
Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. Source: GOC:mtg_15nov05, GO_REF:0000022, GOC:add, ISBN:0781735149
Comment
This term was improved by GO_REF:0000022. It was moved.
History
See term history for GO:0006956 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0006956 from QuickGO

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Ancestors of complement activation (GO:0006956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
complement activation [Inferred positively_regulates relation] positively_regulates (inferred) biological_process (GO:0008150)
complement activation [Inferred is_a relation] is_a (inferred) biological regulation (GO:0065007)
complement activation [Inferred positively_regulates relation] positively_regulates (inferred) immune system process (GO:0002376)
complement activation [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
complement activation [Inferred is_a relation] is_a (inferred) regulation of biological process (GO:0050789)
complement activation [Inferred positively_regulates relation] positively_regulates (inferred) response to stimulus (GO:0050896)
complement activation [Inferred positively_regulates relation] positively_regulates (inferred) immune response (GO:0006955)
complement activation [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
complement activation [Inferred is_a relation] is_a (inferred) positive regulation of biological process (GO:0048518)
complement activation [Inferred is_a relation] is_a (inferred) regulation of immune system process (GO:0002682)
complement activation [Inferred is_a relation] is_a (inferred) regulation of response to stimulus (GO:0048583)
complement activation [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
complement activation [Inferred is_a relation] is_a (inferred) positive regulation of immune system process (GO:0002684)
complement activation [Inferred is_a relation] is_a (inferred) positive regulation of response to stimulus (GO:0048584)
complement activation [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
complement activation [Inferred is_a relation] is_a (inferred) regulation of immune response (GO:0050776)
complement activation [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
complement activation [Inferred is_a relation] is_a (inferred) positive regulation of immune response (GO:0050778)
complement activation [Inferred is_a relation] is_a (inferred) protein metabolic process (GO:0019538)
complement activation [Inferred is_a relation] is_a (inferred) single-organism metabolic process (GO:0044710)
complement activation [is_a relation] is_a  activation of immune response (GO:0002253)
complement activation [is_a relation] is_a  humoral immune response (GO:0006959)
complement activation [is_a relation] is_a  immune effector process (GO:0002252)
complement activation [is_a relation] is_a  protein activation cascade (GO:0072376)
Children of complement activation (GO:0006956)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
activation of membrane attack complex (GO:0001905) [is_a relation] is_a  complement activation
complement activation, alternative pathway (GO:0006957) [is_a relation] is_a  complement activation
complement activation, classical pathway (GO:0006958) [is_a relation] is_a  complement activation
complement activation, lectin pathway (GO:0001867) [is_a relation] is_a  complement activation
negative regulation of complement activation (GO:0045916) [negatively_regulates relation] negatively_regulates  complement activation
positive regulation of complement activation (GO:0045917) [positively_regulates relation] positively_regulates  complement activation
regulation of complement activation (GO:0030449) [regulates relation] regulates  complement activation
suppression by virus of host complement activation (GO:0039573) [negatively_regulates relation] negatively_regulates  complement activation