AmiGO 2: Term Details for "receptor-mediated endocytosis" (GO:0006898)

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Term Information

Accession: GO:0006898
Name: receptor-mediated endocytosis
Ontology: biological_process
Synonyms: receptor mediated endocytosis
Alternate IDs: None
Definition: An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. Source: ISBN:0716731363, GOC:mah
Comment: None
History: See term history for GO:0006898 at QuickGO
Subset: None
Related: Link to all genes and gene products annotated to receptor-mediated endocytosis.; Link to all direct and indirect annotations to receptor-mediated endocytosis.; Link to all direct and indirect annotations download (limited to first 10,000) for receptor-mediated endocytosis.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0006810 transport
GO:0016192 vesicle-mediated transport
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0038024 cargo receptor activity
GO:0072583 clathrin-dependent endocytosis
GO:0098748 endocytic adaptor activity
GO:0048261 negative regulation of receptor-mediated endocytosis
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0031623 receptor internalization
GO:0090118 receptor-mediated endocytosis involved in cholesterol transport
GO:0019065 receptor-mediated endocytosis of virus by host cell
GO:0048259 regulation of receptor-mediated endocytosis

Parents of receptor-mediated endocytosis (GO:0006898)

subject	relation	object
receptor-mediated endocytosis	is_a	endocytosis (GO:0006897)

Children of receptor-mediated endocytosis (GO:0006898)

subject	relation	object
regulation of receptor-mediated endocytosis (GO:0048259)	regulates	receptor-mediated endocytosis
positive regulation of receptor-mediated endocytosis (GO:0048260)	positively_regulates	receptor-mediated endocytosis
plasma lipoprotein particle clearance (GO:0034381)	has_part	receptor-mediated endocytosis
endocytic adaptor activity (GO:0098748)	part_of	receptor-mediated endocytosis
clathrin-dependent endocytosis (GO:0072583)	is_a	receptor-mediated endocytosis
receptor-mediated endocytosis of virus by host cell (GO:0019065)	is_a	receptor-mediated endocytosis
negative regulation of receptor-mediated endocytosis (GO:0048261)	negatively_regulates	receptor-mediated endocytosis
receptor internalization (GO:0031623)	is_a	receptor-mediated endocytosis
receptor-mediated endocytosis involved in cholesterol transport (GO:0090118)	is_a	receptor-mediated endocytosis
cargo receptor activity (GO:0038024)	part_of	receptor-mediated endocytosis

Reactome: REACT_104437; REACT_90294; REACT_103823; REACT_83320; REACT_106851; REACT_30705; REACT_84451; REACT_82595; REACT_86311; REACT_31638; REACT_84978; REACT_111177; REACT_6934; REACT_34027; REACT_78761; REACT_6810; REACT_50874; REACT_93284; REACT_50314; REACT_6775; REACT_112262; REACT_91303; REACT_96679; REACT_91595; REACT_90065; REACT_87254; REACT_100248; REACT_28736; REACT_110306; REACT_84983; REACT_106981; REACT_6849; REACT_114755; REACT_6924; REACT_98265; REACT_81516; REACT_30731; REACT_6720; REACT_113143; REACT_115520; REACT_114157; REACT_110472; REACT_94912; REACT_33281; REACT_84153; REACT_114061; REACT_109308; REACT_84233; REACT_87301; REACT_100330; REACT_107880; REACT_29541; REACT_81206; REACT_110785; REACT_30568; REACT_33230; REACT_80639; REACT_6951; REACT_115471; REACT_115278; REACT_114861; REACT_90795; REACT_95536; REACT_103978; REACT_93519; REACT_85895; REACT_113715; REACT_107413; REACT_84963; REACT_82541; REACT_83479; REACT_105792; REACT_81850; REACT_30278; REACT_78454; REACT_84602; REACT_83238; REACT_6901; REACT_80964; REACT_107174; REACT_31404; REACT_99018; REACT_6940; REACT_6860; REACT_77527
Wikipedia: Receptor-mediated_endocytosis