AmiGO 2: Term Details for "translational initiation" (GO:0006413)

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Term Information

Accession: GO:0006413
Name: translational initiation
Ontology: biological_process
Synonyms: translation initiation, biopolymerisation, biopolymerization, protein synthesis initiation
Alternate IDs: GO:0006440, GO:0006454
Definition: The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. Source: ISBN:019879276X
Comment: None
History: See term history for GO:0006413 at QuickGO
Subset: gosubset_prok; goslim_yeast
Related: Link to all genes and gene products annotated to translational initiation.; Link to all direct and indirect annotations to translational initiation.; Link to all direct and indirect annotations download (limited to first 10,000) for translational initiation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0044249 cellular biosynthetic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0043603 cellular amide metabolic process
GO:0044271 cellular nitrogen compound biosynthetic process
GO:0043170 macromolecule metabolic process
GO:1901576 organic substance biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0043604 amide biosynthetic process
GO:0044260 cellular macromolecule metabolic process
GO:0009059 macromolecule biosynthetic process
GO:1901566 organonitrogen compound biosynthetic process
GO:0006518 peptide metabolic process
GO:0019538 protein metabolic process
GO:0034645 cellular macromolecule biosynthetic process
GO:0044267 cellular protein metabolic process
GO:0010467 gene expression
GO:0043043 peptide biosynthetic process
GO:0006412 translation
GO:0006413 translational initiation
GO:0002183 cytoplasmic translational initiation
GO:0001677 formation of translation initiation ternary complex
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0070124 mitochondrial translational initiation
GO:0045947 negative regulation of translational initiation
GO:0045948 positive regulation of translational initiation
GO:0006446 regulation of translational initiation
GO:0070992 translation initiation complex
GO:0003743 translation initiation factor activity

Parents of translational initiation (GO:0006413)

subject	relation	object
translational initiation	starts_with	formation of translation initiation ternary complex (GO:0001677)
translational initiation	is_a	cellular metabolic process (GO:0044237)
translational initiation	part_of	translation (GO:0006412)

Children of translational initiation (GO:0006413)

subject	relation	object
translation (GO:0006412)	starts_with	translational initiation
translation initiation complex (GO:0070992)	capable_of_part_of	translational initiation
cytoplasmic translational initiation (GO:0002183)	is_a	translational initiation
methionyl-tRNA formyltransferase activity (GO:0004479)	part_of	translational initiation
regulation of translational initiation (GO:0006446)	regulates	translational initiation
positive regulation of translational initiation (GO:0045948)	positively_regulates	translational initiation
translation initiation factor activity (GO:0003743)	part_of	translational initiation
negative regulation of translational initiation (GO:0045947)	negatively_regulates	translational initiation
mitochondrial translational initiation (GO:0070124)	is_a	translational initiation
formation of translation initiation ternary complex (GO:0001677)	part_of	translational initiation

Reactome: REACT_91066; REACT_85780; REACT_101789; REACT_97707; REACT_88031; REACT_33969; REACT_30389; REACT_29447; REACT_95293; REACT_2159; REACT_77252; REACT_104290; REACT_79705; REACT_34354; REACT_98138; REACT_99004; REACT_95685; REACT_95552