Term Information [More information on nucleotide-excision repair]

Accession
GO:0006289
Name
nucleotide-excision repair
Ontology
biological_process
Synonyms
alt. id: GO:0045001
NER, pyrimidine-dimer repair, DNA damage excision, intrastrand cross-link repair
Definition
A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). Source: PMID:10197977
Comment
Note that although intrastrand cross-link repair is not exactly synonymous with nucleotide excision repair, nucleotide excision repair includes the repair of intrastrand cross-links. The synonym field is being used to reflect the broad substrate specificity of nucleotide excision repair.
History
See term history for GO:0006289 at QuickGO
Subset
gosubset_prok
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0006289 from QuickGO

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Ancestors of nucleotide-excision repair (GO:0006289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) biological_process (GO:0008150)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular process (GO:0009987)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) metabolic process (GO:0008152)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular metabolic process (GO:0044237)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) nitrogen compound metabolic process (GO:0006807)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular aromatic compound metabolic process (GO:0006725)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular nitrogen compound metabolic process (GO:0034641)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) heterocycle metabolic process (GO:0046483)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) organic cyclic compound metabolic process (GO:1901360)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) primary metabolic process (GO:0044238)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) response to stimulus (GO:0050896)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular response to stimulus (GO:0051716)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) macromolecule metabolic process (GO:0043170)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) nucleobase-containing compound metabolic process (GO:0006139)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) response to stress (GO:0006950)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular macromolecule metabolic process (GO:0044260)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular response to stress (GO:0033554)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) nucleic acid metabolic process (GO:0090304)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) single-organism process (GO:0044699)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) cellular response to DNA damage stimulus (GO:0006974)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) DNA metabolic process (GO:0006259)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) single-organism cellular process (GO:0044763)
nucleotide-excision repair [Inferred is_a relation] is_a (inferred) single-organism metabolic process (GO:0044710)
nucleotide-excision repair [is_a relation] is_a  DNA repair (GO:0006281)
Children of nucleotide-excision repair (GO:0006289)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
global genome nucleotide-excision repair (GO:0070911) [is_a relation] is_a  nucleotide-excision repair
nucleotide-excision repair complex (GO:0000109) [capable_of part of relation] capable_of part of  nucleotide-excision repair
nucleotide-excision repair involved in interstrand cross-link repair (GO:1901255) [is_a relation] is_a  nucleotide-excision repair
nucleotide-excision repair, DNA damage recognition (GO:0000715) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, DNA damage removal (GO:0000718) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, DNA duplex unwinding (GO:0000717) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, DNA gap filling (GO:0006297) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, DNA incision (GO:0033683) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, preincision complex assembly (GO:0006294) [part_of relation] part_of  nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization (GO:0006293) [part_of relation] part_of  nucleotide-excision repair
pyrimidine dimer repair by nucleotide-excision repair (GO:0000720) [is_a relation] is_a  nucleotide-excision repair
regulation of nucleotide-excision repair (GO:2000819) [regulates relation] regulates  nucleotide-excision repair
transcription-coupled nucleotide-excision repair (GO:0006283) [is_a relation] is_a  nucleotide-excision repair