Term Information [More information on tricarboxylic acid cycle]

Accession
GO:0006099
Name
tricarboxylic acid cycle
Ontology
biological_process
Synonyms
Krebs cycle, TCA cycle, citric acid cycle
Definition
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. Source: ISBN:0198506732
Comment
None
History
See term history for GO:0006099 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0006099 from QuickGO

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Ancestors of tricarboxylic acid cycle (GO:0006099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) single-organism metabolic process (GO:0044710)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) organic substance metabolic process (GO:0071704)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) small molecule metabolic process (GO:0044281)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) organic acid metabolic process (GO:0006082)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) generation of precursor metabolites and energy (GO:0006091)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) oxidation-reduction process (GO:0055114)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) oxoacid metabolic process (GO:0043436)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) carboxylic acid metabolic process (GO:0019752)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) energy derivation by oxidation of organic compounds (GO:0015980)
tricarboxylic acid cycle [Inferred part_of relation] part_of (inferred) cellular respiration (GO:0045333)
tricarboxylic acid cycle [Inferred is_a relation] is_a (inferred) tricarboxylic acid metabolic process (GO:0072350)
tricarboxylic acid cycle [part_of relation] part_of  aerobic respiration (GO:0009060)
tricarboxylic acid cycle [is_a relation] is_a  citrate metabolic process (GO:0006101)
tricarboxylic acid cycle [is_a relation] is_a  primary metabolic process (GO:0044238)
Children of tricarboxylic acid cycle (GO:0006099)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
reductive tricarboxylic acid cycle (GO:0019643) [is_a relation] is_a  tricarboxylic acid cycle