Term Information [More information on cytoplasmic dynein complex]

Accession
GO:0005868
Name
cytoplasmic dynein complex
Ontology
cellular_component
Synonyms
cytoplasmic dynein heavy chain, cytoplasmic dynein intermediate chain, cytoplasmic dynein intermediate light chain, cytoplasmic dynein light chain
Definition
Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains. Source: GOC:krc, PMID:12600311, GOC:mah, GOC:cilia, GOC:hla
Comment
Note that this term is labelled based on phylogenetic classification and community usage, rather than strict cellular localization. Cytoplasmic dynein complexes may contain ciliary dyneins; therefore the term is not linked to 'cytoplasm'. Cytoplasmic dynein complexes do not contain axonemal dyneins; see GO:0005858 axonemal dynein complex.
History
See term history for GO:0005868 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0005868 from QuickGO

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Ancestors of cytoplasmic dynein complex (GO:0005868)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
cytoplasmic dynein complex [Inferred capable_of part of relation] capable_of part of (inferred) molecular_function (GO:0003674)
cytoplasmic dynein complex [Inferred capable_of relation] capable_of (inferred) catalytic activity (GO:0003824)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
cytoplasmic dynein complex [Inferred capable_of relation] capable_of (inferred) hydrolase activity (GO:0016787)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
cytoplasmic dynein complex [Inferred capable_of relation] capable_of (inferred) hydrolase activity, acting on acid anhydrides (GO:0016817)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
cytoplasmic dynein complex [Inferred capable_of part of relation] capable_of part of (inferred) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) non-membrane-bounded organelle (GO:0043228)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) intracellular non-membrane-bounded organelle (GO:0043232)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
cytoplasmic dynein complex [Inferred capable_of relation] capable_of (inferred) pyrophosphatase activity (GO:0016462)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) cytoskeleton (GO:0005856)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
cytoplasmic dynein complex [Inferred capable_of relation] capable_of (inferred) nucleoside-triphosphatase activity (GO:0017111)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) cytoskeletal part (GO:0044430)
cytoplasmic dynein complex [Inferred part_of relation] part_of (inferred) microtubule cytoskeleton (GO:0015630)
cytoplasmic dynein complex [Inferred capable_of part of relation] capable_of part of (inferred) motor activity (GO:0003774)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
cytoplasmic dynein complex [Inferred is_a relation] is_a (inferred) microtubule associated complex (GO:0005875)
cytoplasmic dynein complex [Inferred capable_of part of relation] capable_of part of (inferred) microtubule motor activity (GO:0003777)
cytoplasmic dynein complex [is_a relation] is_a  dynein complex (GO:0030286)

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