Term Information [More information on anaphase-promoting complex]

Accession
GO:0005680
Name
anaphase-promoting complex
Ontology
cellular_component
Synonyms
anaphase promoting complex, cyclosome, APC
Definition
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. Source: PMID:10611969, PMID:10465783, GOC:jh, GOC:vw
Comment
Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.
History
See term history for GO:0005680 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0005680 from QuickGO

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Ancestors of anaphase-promoting complex (GO:0005680)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) metabolic process (GO:0008152)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular process (GO:0009987)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) organic substance metabolic process (GO:0071704)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular metabolic process (GO:0044237)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule metabolic process (GO:0043170)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) primary metabolic process (GO:0044238)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular macromolecule metabolic process (GO:0044260)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) macromolecule modification (GO:0043412)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) protein metabolic process (GO:0019538)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein metabolic process (GO:0044267)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification process (GO:0036211)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) cellular protein modification process (GO:0006464)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) molecular_function (GO:0003674)
anaphase-promoting complex [Inferred capable_of relation] capable_of (inferred) catalytic activity (GO:0003824)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) intracellular (GO:0005622)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation or removal (GO:0070647)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) intracellular part (GO:0044424)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) organelle (GO:0043226)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) protein modification by small protein conjugation (GO:0032446)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) transferase activity (GO:0016740)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) intracellular organelle (GO:0043229)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) membrane-bounded organelle (GO:0043227)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) protein ubiquitination (GO:0016567)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-like protein transferase activity (GO:0019787)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) catalytic complex (GO:1902494)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) intracellular membrane-bounded organelle (GO:0043231)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) organelle part (GO:0044422)
anaphase-promoting complex [Inferred capable_of relation] capable_of (inferred) ubiquitin-like protein ligase activity (GO:0061659)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin-protein transferase activity (GO:0004842)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) intracellular organelle part (GO:0044446)
anaphase-promoting complex [Inferred part_of relation] part_of (inferred) nucleus (GO:0005634)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) transferase complex (GO:1990234)
anaphase-promoting complex [Inferred capable_of part of relation] capable_of part of (inferred) ubiquitin protein ligase activity (GO:0061630)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) nuclear part (GO:0044428)
anaphase-promoting complex [Inferred is_a relation] is_a (inferred) ubiquitin ligase complex (GO:0000151)
anaphase-promoting complex [is_a relation] is_a  cullin-RING ubiquitin ligase complex (GO:0031461)
anaphase-promoting complex [is_a relation] is_a  nuclear ubiquitin ligase complex (GO:0000152)

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