Term Information [More information on membrane attack complex]

Accession
GO:0005579
Name
membrane attack complex
Ontology
cellular_component
Synonyms
MAC, TCC, terminal complement complex, membrane attack complex protein alphaM chain, membrane attack complex protein beta2 chain
Definition
A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow. Source: ISBN:0198547684, ISBN:068340007X, GOC:add, ISBN:0781735149
Comment
None
History
See term history for GO:0005579 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0005579 from QuickGO

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Ancestors of membrane attack complex (GO:0005579)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
membrane attack complex [Inferred part_of relation] part_of (inferred) cellular_component (GO:0005575)
membrane attack complex [Inferred part_of relation] part_of (inferred) cell (GO:0005623)
membrane attack complex [Inferred part_of relation] part_of (inferred) cell part (GO:0044464)
membrane attack complex [Inferred part_of relation] part_of (inferred) cell periphery (GO:0071944)
membrane attack complex [Inferred part_of relation] part_of (inferred) membrane (GO:0016020)
membrane attack complex [Inferred is_a relation] is_a (inferred) macromolecular complex (GO:0032991)
membrane attack complex [Inferred part_of relation] part_of (inferred) membrane part (GO:0044425)
membrane attack complex [Inferred part_of relation] part_of (inferred) plasma membrane (GO:0005886)
membrane attack complex [Inferred capable_of part of relation] capable_of part of (inferred) biological_process (GO:0008150)
membrane attack complex [Inferred part_of relation] part_of (inferred) intrinsic component of membrane (GO:0031224)
membrane attack complex [Inferred part_of relation] part_of (inferred) plasma membrane part (GO:0044459)
membrane attack complex [Inferred is_a relation] is_a (inferred) protein complex (GO:0043234)
membrane attack complex [Inferred capable_of part of relation] capable_of part of (inferred) cell killing (GO:0001906)
membrane attack complex [Inferred part_of relation] part_of (inferred) integral component of membrane (GO:0016021)
membrane attack complex [Inferred part_of relation] part_of (inferred) intrinsic component of plasma membrane (GO:0031226)
membrane attack complex [Inferred is_a relation] is_a (inferred) membrane protein complex (GO:0098796)
membrane attack complex [Inferred capable_of part of relation] capable_of part of (inferred) single-organism process (GO:0044699)
membrane attack complex [capable_of part of relation] capable_of part of  complement-dependent cytotoxicity (GO:0097278)
membrane attack complex [part_of relation] part_of  integral component of plasma membrane (GO:0005887)
membrane attack complex [is_a relation] is_a  plasma membrane protein complex (GO:0098797)
membrane attack complex [is_a relation] is_a  pore complex (GO:0046930)

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