Term Information [More information on Ran guanyl-nucleotide exchange factor activity]

Accession
GO:0005087
Name
Ran guanyl-nucleotide exchange factor activity
Ontology
molecular_function
Synonyms
RCC1
Definition
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. Source: GOC:mah
Comment
None
History
See term history for GO:0005087 at QuickGO
Subset
None
Community
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Graph of GO:0005087 from QuickGO

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Ancestors of Ran guanyl-nucleotide exchange factor activity (GO:0005087)
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Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) molecular_function (GO:0003674)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) catalytic activity (GO:0003824)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) binding (GO:0005488)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) hydrolase activity (GO:0016787)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) heterocyclic compound binding (GO:1901363)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) hydrolase activity, acting on acid anhydrides (GO:0016817)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) organic cyclic compound binding (GO:0097159)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) biological regulation (GO:0065007)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) nucleoside phosphate binding (GO:1901265)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) small molecule binding (GO:0036094)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) carbohydrate derivative binding (GO:0097367)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) nucleotide binding (GO:0000166)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) pyrophosphatase activity (GO:0016462)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) regulation of molecular function (GO:0065009)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) nucleoside binding (GO:0001882)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) nucleoside-triphosphatase activity (GO:0017111)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) positive regulation of molecular function (GO:0044093)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) purine nucleotide binding (GO:0017076)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) regulation of catalytic activity (GO:0050790)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) ribonucleotide binding (GO:0032553)
Ran guanyl-nucleotide exchange factor activity [Inferred related_to relation] related_to (inferred) GTPase activity (GO:0003924)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) guanyl nucleotide binding (GO:0019001)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) ion binding (GO:0043167)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) positive regulation of catalytic activity (GO:0043085)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) purine nucleoside binding (GO:0001883)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) purine ribonucleotide binding (GO:0032555)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) regulation of hydrolase activity (GO:0051336)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) ribonucleoside binding (GO:0032549)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) anion binding (GO:0043168)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) guanyl ribonucleotide binding (GO:0032561)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) positive regulation of hydrolase activity (GO:0051345)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) purine ribonucleoside binding (GO:0032550)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) regulation of GTPase activity (GO:0043087)
Ran guanyl-nucleotide exchange factor activity [Inferred negatively_regulates relation] negatively_regulates (inferred) GDP binding (GO:0019003)
Ran guanyl-nucleotide exchange factor activity [Inferred is_a relation] is_a (inferred) molecular function regulator (GO:0098772)
Ran guanyl-nucleotide exchange factor activity [Inferred part_of relation] part_of (inferred) positive regulation of GTPase activity (GO:0043547)
Ran guanyl-nucleotide exchange factor activity [Inferred is_a relation] is_a (inferred) guanyl-nucleotide exchange factor activity (GO:0005085)
Ran guanyl-nucleotide exchange factor activity [is_a relation] is_a  Ras guanyl-nucleotide exchange factor activity (GO:0005088)

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