Term Information [More information on chemokine receptor activity]

Accession
GO:0004950
Name
chemokine receptor activity
Ontology
molecular_function
Synonyms
None
Definition
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. Source: GOC:rl, IUPHAR_GPCR:1280, PMID:12183377, PMID:8662823, http://en.wikipedia.org/wiki/Chemokine, GOC:signaling, GOC:BHF
Comment
None
History
See term history for GO:0004950 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0004950 from QuickGO

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Ancestors of chemokine receptor activity (GO:0004950)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chemokine receptor activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) biological regulation (GO:0065007)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) single-organism process (GO:0044699)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) regulation of biological process (GO:0050789)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) response to stimulus (GO:0050896)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) signaling (GO:0023052)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) single-organism cellular process (GO:0044763)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cell communication (GO:0007154)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cellular response to stimulus (GO:0051716)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) regulation of cellular process (GO:0050794)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) single organism signaling (GO:0044700)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) molecular transducer activity (GO:0060089)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) signal transduction (GO:0007165)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) receptor activity (GO:0004872)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) response to chemical (GO:0042221)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) signal transducer activity (GO:0004871)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cellular response to chemical stimulus (GO:0070887)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) response to organic substance (GO:0010033)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) signaling receptor activity (GO:0038023)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) transmembrane receptor activity (GO:0099600)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cellular response to organic substance (GO:0071310)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) G-protein coupled receptor signaling pathway (GO:0007186)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) response to cytokine (GO:0034097)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) transmembrane signaling receptor activity (GO:0004888)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cell surface receptor signaling pathway (GO:0007166)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cellular response to cytokine stimulus (GO:0071345)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) G-protein coupled receptor activity (GO:0004930)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) peptide receptor activity (GO:0001653)
chemokine receptor activity [Inferred part_of relation] part_of (inferred) cytokine-mediated signaling pathway (GO:0019221)
chemokine receptor activity [Inferred is_a relation] is_a (inferred) G-protein coupled peptide receptor activity (GO:0008528)
chemokine receptor activity [part_of relation] part_of  chemokine-mediated signaling pathway (GO:0070098)
chemokine receptor activity [is_a relation] is_a  cytokine receptor activity (GO:0004896)
chemokine receptor activity [is_a relation] is_a  G-protein coupled chemoattractant receptor activity (GO:0001637)
Children of chemokine receptor activity (GO:0004950)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
C-C chemokine receptor activity (GO:0016493) [is_a relation] is_a  chemokine receptor activity
C-X-C chemokine receptor activity (GO:0016494) [is_a relation] is_a  chemokine receptor activity
C-X3-C chemokine receptor activity (GO:0016495) [is_a relation] is_a  chemokine receptor activity
None.