Term Information [More information on uracil DNA N-glycosylase activity]

Accession
GO:0004844
Name
uracil DNA N-glycosylase activity
Ontology
molecular_function
Synonyms
uracil-DNA glycosylase activity
Definition
Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. Source: PMID:9224623, GOC:elh, GOC:pr
Comment
None
History
See term history for GO:0004844 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004844 from QuickGO

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Ancestors of uracil DNA N-glycosylase activity (GO:0004844)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on glycosyl bonds (GO:0016798)
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
uracil DNA N-glycosylase activity [Inferred is_a relation] is_a (inferred) DNA N-glycosylase activity (GO:0019104)
uracil DNA N-glycosylase activity [is_a relation] is_a  deaminated base DNA N-glycosylase activity (GO:0097506)
Children of uracil DNA N-glycosylase activity (GO:0004844)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G/U mismatch-specific uracil-DNA glycosylase activity (GO:0043739) [is_a relation] is_a  uracil DNA N-glycosylase activity
single-strand selective uracil DNA N-glycosylase activity (GO:0017065) [is_a relation] is_a  uracil DNA N-glycosylase activity