Term Information [More information on ubiquitin-specific protease activity]

Accession
GO:0004843
Name
ubiquitin-specific protease activity
Ontology
molecular_function
Synonyms
deubiquitinase, deubiquitinase activity, deubiquitinating enzyme, deubiquitylase, ubiquitin C-terminal hydrolase activity, ubiquitin hydrolase activity, UBP, UCH2
Definition
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. Source: ISBN:0120793709, GOC:jh2
Comment
None
History
See term history for GO:0004843 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0004843 from QuickGO

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Ancestors of ubiquitin-specific protease activity (GO:0004843)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
ubiquitin-specific protease activity [Inferred part_of relation] part_of (inferred) proteolysis (GO:0006508)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) peptidase activity (GO:0008233)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) peptidase activity, acting on L-amino acid peptides (GO:0070011)
ubiquitin-specific protease activity [Inferred is_a relation] is_a (inferred) cysteine-type peptidase activity (GO:0008234)
ubiquitin-specific protease activity [is_a relation] is_a  ubiquitin-like protein-specific protease activity (GO:0019783)
ubiquitin-specific protease activity [is_a relation] is_a  ubiquitinyl hydrolase activity (GO:0036459)
Children of ubiquitin-specific protease activity (GO:0004843)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Lys48-specific deubiquitinase activity (GO:1990380) [is_a relation] is_a  ubiquitin-specific protease activity
Lys63-specific deubiquitinase activity (GO:0061578) [is_a relation] is_a  ubiquitin-specific protease activity
negative regulation of ubiquitin-specific protease activity (GO:2000157) [negatively_regulates relation] negatively_regulates  ubiquitin-specific protease activity
positive regulation of ubiquitin-specific protease activity (GO:2000158) [positively_regulates relation] positively_regulates  ubiquitin-specific protease activity
regulation of ubiquitin-specific protease activity (GO:2000152) [regulates relation] regulates  ubiquitin-specific protease activity
ubiquitin-specific protease activity involved in negative regulation of ERAD pathway (GO:1904455) [is_a relation] is_a  ubiquitin-specific protease activity
ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol (GO:1904265) [is_a relation] is_a  ubiquitin-specific protease activity
ubiquitin-specific protease activity involved in positive regulation of ERAD pathway (GO:1904454) [is_a relation] is_a  ubiquitin-specific protease activity