Term Information [More information on ubiquitin activating enzyme activity]

Accession
GO:0004839
Name
ubiquitin activating enzyme activity
Ontology
molecular_function
Synonyms
E1
Definition
Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. Source: GOC:BioGRID, http://www.bostonbiochem.com/E-301.html, PMID:10072378
Comment
None
History
See term history for GO:0004839 at QuickGO
Subset
None
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
Contact the GO Helpdesk if you find mistakes or have concerns about the data you find here.
Contacting server...
View this term in QuickGO.

Graph of GO:0004839 from QuickGO

Additional external viewing options
Additional internal viewing options
Ancestors of ubiquitin activating enzyme activity (GO:0004839)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) cellular macromolecule metabolic process (GO:0044260)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) macromolecule modification (GO:0043412)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) protein metabolic process (GO:0019538)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) cellular protein metabolic process (GO:0044267)
ubiquitin activating enzyme activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) protein modification process (GO:0036211)
ubiquitin activating enzyme activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) cellular protein modification process (GO:0006464)
ubiquitin activating enzyme activity [Inferred is_a relation] is_a (inferred) ligase activity (GO:0016874)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) protein modification by small protein conjugation or removal (GO:0070647)
ubiquitin activating enzyme activity [Inferred is_a relation] is_a (inferred) ligase activity, forming carbon-sulfur bonds (GO:0016877)
ubiquitin activating enzyme activity [Inferred part_of relation] part_of (inferred) protein modification by small protein conjugation (GO:0032446)
ubiquitin activating enzyme activity [part_of relation] part_of  protein ubiquitination (GO:0016567)
ubiquitin activating enzyme activity [is_a relation] is_a  small protein activating enzyme activity (GO:0008641)

This term has no children.