Term Information [More information on Rab geranylgeranyltransferase activity]

Accession
GO:0004663
Name
Rab geranylgeranyltransferase activity
Ontology
molecular_function
Synonyms
GGTase-II activity, GGTaseII activity, Rab-protein geranylgeranyltransferase activity, RabGGTase activity, geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity, protein geranylgeranyltransferase type II activity, type II protein geranyl-geranyltransferase activity
Definition
Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. Source: PMID:8621375, GOC:mah, EC:2.5.1.60
Comment
None
History
See term history for GO:0004663 at QuickGO
Subset
None
Community
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Feedback
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Graph of GO:0004663 from QuickGO

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Ancestors of Rab geranylgeranyltransferase activity (GO:0004663)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) transferase activity (GO:0016740)
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765)
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) prenyltransferase activity (GO:0004659)
Rab geranylgeranyltransferase activity [Inferred is_a relation] is_a (inferred) protein prenyltransferase activity (GO:0008318)
Rab geranylgeranyltransferase activity [is_a relation] is_a  protein geranylgeranyltransferase activity (GO:0004661)
Children of Rab geranylgeranyltransferase activity (GO:0004663)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Rab-protein geranylgeranyltransferase complex (GO:0005968) [capable_of relation] capable_of  Rab geranylgeranyltransferase activity