Term Information [More information on RNA-DNA hybrid ribonuclease activity]

Accession
GO:0004523
Name
RNA-DNA hybrid ribonuclease activity
Ontology
molecular_function
Synonyms
alt. id: GO:0004524
RNA*DNA hybrid ribonucleotidohydrolase activity, RNase H activity, calf thymus ribonuclease H activity, hybrid nuclease activity, hybrid ribonuclease activity, hybridase (ribonuclease H), hybridase activity, ribonuclease H activity, endoribonuclease H, endoribonuclease H (calf thymus), RNase H1 activity, RNase H2 activity, RNase H3 activity, endoribonuclease0 H activity, ribonuclease H1 activity, ribonuclease H2 activity, ribonuclease H3 activity
Definition
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. Source: EC:3.1.26.4
Comment
Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species.
History
See term history for GO:0004523 at QuickGO
Subset
gosubset_prok
Community
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Feedback
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Graph of GO:0004523 from QuickGO

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Ancestors of RNA-DNA hybrid ribonuclease activity (GO:0004523)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) nitrogen compound metabolic process (GO:0006807)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) cellular aromatic compound metabolic process (GO:0006725)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) cellular nitrogen compound metabolic process (GO:0034641)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) heterocycle metabolic process (GO:0046483)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) organic cyclic compound metabolic process (GO:1901360)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) nucleobase-containing compound metabolic process (GO:0006139)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) cellular macromolecule metabolic process (GO:0044260)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) nucleic acid metabolic process (GO:0090304)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) hydrolase activity, acting on ester bonds (GO:0016788)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) nucleic acid phosphodiester bond hydrolysis (GO:0090305)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) RNA metabolic process (GO:0016070)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) nuclease activity (GO:0004518)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) RNA phosphodiester bond hydrolysis (GO:0090501)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) endonuclease activity (GO:0004519)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) ribonuclease activity (GO:0004540)
RNA-DNA hybrid ribonuclease activity [Inferred part_of relation] part_of (inferred) RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (GO:0016893)
RNA-DNA hybrid ribonuclease activity [Inferred is_a relation] is_a (inferred) endoribonuclease activity (GO:0004521)
RNA-DNA hybrid ribonuclease activity [is_a relation] is_a  endoribonuclease activity, producing 5'-phosphomonoesters (GO:0016891)

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