Term Information [More information on nuclease activity]

Accession
GO:0004518
Name
nuclease activity
Ontology
molecular_function
Synonyms
None
Definition
Catalysis of the hydrolysis of ester linkages within nucleic acids. Source: ISBN:0198547684
Comment
Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.
History
See term history for GO:0004518 at QuickGO
Subset
gosubset_prok
goslim_generic
goslim_plant
goslim_metagenomics
goslim_chembl
goslim_yeast
Community
GN Add usage comments for this term on the GONUTS wiki.
Feedback
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Graph of GO:0004518 from QuickGO

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Ancestors of nuclease activity (GO:0004518)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclease activity [Inferred part_of relation] part_of (inferred) biological_process (GO:0008150)
nuclease activity [Inferred part_of relation] part_of (inferred) cellular process (GO:0009987)
nuclease activity [Inferred part_of relation] part_of (inferred) metabolic process (GO:0008152)
nuclease activity [Inferred part_of relation] part_of (inferred) cellular metabolic process (GO:0044237)
nuclease activity [Inferred part_of relation] part_of (inferred) nitrogen compound metabolic process (GO:0006807)
nuclease activity [Inferred part_of relation] part_of (inferred) organic substance metabolic process (GO:0071704)
nuclease activity [Inferred part_of relation] part_of (inferred) cellular aromatic compound metabolic process (GO:0006725)
nuclease activity [Inferred part_of relation] part_of (inferred) cellular nitrogen compound metabolic process (GO:0034641)
nuclease activity [Inferred part_of relation] part_of (inferred) heterocycle metabolic process (GO:0046483)
nuclease activity [Inferred is_a relation] is_a (inferred) molecular_function (GO:0003674)
nuclease activity [Inferred part_of relation] part_of (inferred) organic cyclic compound metabolic process (GO:1901360)
nuclease activity [Inferred part_of relation] part_of (inferred) primary metabolic process (GO:0044238)
nuclease activity [Inferred is_a relation] is_a (inferred) catalytic activity (GO:0003824)
nuclease activity [Inferred part_of relation] part_of (inferred) macromolecule metabolic process (GO:0043170)
nuclease activity [Inferred part_of relation] part_of (inferred) nucleobase-containing compound metabolic process (GO:0006139)
nuclease activity [Inferred is_a relation] is_a (inferred) hydrolase activity (GO:0016787)
nuclease activity [Inferred part_of relation] part_of (inferred) nucleic acid metabolic process (GO:0090304)
nuclease activity [is_a relation] is_a  hydrolase activity, acting on ester bonds (GO:0016788)
nuclease activity [part_of relation] part_of  nucleic acid phosphodiester bond hydrolysis (GO:0090305)
Children of nuclease activity (GO:0004518)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
deoxyribonuclease activity (GO:0004536) [is_a relation] is_a  nuclease activity
endonuclease activity (GO:0004519) [is_a relation] is_a  nuclease activity
exonuclease activity (GO:0004527) [is_a relation] is_a  nuclease activity
negative regulation of nuclease activity (GO:0032074) [negatively_regulates relation] negatively_regulates  nuclease activity
oligonucleotidase activity (GO:0008946) [is_a relation] is_a  nuclease activity
positive regulation of nuclease activity (GO:0032075) [positively_regulates relation] positively_regulates  nuclease activity
regulation of nuclease activity (GO:0032069) [regulates relation] regulates  nuclease activity
ribonuclease activity (GO:0004540) [is_a relation] is_a  nuclease activity
EC
3.1.-.-